In an open study, eight patientswith Lewy body dementiaassociated with psychotic and behavioral difficulties were given olanzapine 2.5–7.5mg [30]. Three of the eight could not tolerate olanzapine, even at the lowest dose, two had a clear improvement in psychotic and behavioral symptoms, and thre...
For 24 months, we monitored 68 outpatients suffering from Alzheimer's disease, vascular dementia, frontal lobe dementia, Parkinson dementia complex, and Lewy body disease. Our purpose was to identify the role and efficacy of olanzapine and the side effects which emerged during the treatment of ...
compounds on each plate were compared to control wells on the same plate that received Aβ42, apoE4, ThT, and DMSO. Unlike in the exploratory screen, the optimal concentrations of 20 μM Aβ42, 1 nM apoE, and 15 μM ThT were used in the HTS assay because this assay was developed a...
compounds on each plate were compared to control wells on the same plate that received Aβ42, apoE4, ThT, and DMSO. Unlike in the exploratory screen, the optimal concentrations of 20 μM Aβ42, 1 nM apoE, and 15 μM ThT were used in the HTS assay because this assay was developed a...
fromAlzheimer'sdisease,vasculardementia,frontallobedementia,Parkinsondementiacomplex,andLewybodydiseaseOurpurposewastoidentifytheroleandefficacyofolanzapineandthesideeffectswhichemergedduringthetreatmentofbehavioralalterationresultingfromfiveetiologicalcausesThispaperwilldiscusstheresultsofthisstudy,andwillprovideanoverviewofthe...