Olanzapine may cause serious side effects such as an increased risk of death or stroke in elderly patients with dementia, a higher risk of suicide when taken with fluoxetine, metabolic changes, tardive dyskinesia, low blood pressure, and blood cell disorders. See the warnings below for a full ...
demonstrated geriatric-specific problems that would limit the usefulness of olanzapine in the elderly. However, elderly patients are more likely to have dementia or age-related liver, kidney, or heart problems, which may require caution or an adjustment in the dose for patients receiving olanzapine....
IM olanzapine effectively controls agitation in patients with dementia,Olanzapine, therapeutic useAgitation, treatmentInpharma Weekly -doi:10.2165/00128413-200112770-00032NoneSpringer International PublishingInpharma Weekly
Background Aggression, agitation or psychosis occur in the majority of people with dementia at some point in the illness. There have been a number of trial... CG Ballard,J Waite,J Birks - 《Cochrane Database of Systematic Reviews》 被引量: 266发表: 2006年 Olanzapine in the treatment of ...
What Are Warnings and Precautions for Olanzapine? Warnings Not approved for dementia-related psychosis; elderly patients with dementia-related psychosis who are treated withantipsychoticdrugs are at increased risk of death, as shown in short-term controlled trials; in these trials, deaths appeared to ...
In placebo-controlled 6-week trials the most common adverse events (reported by at least 10% of olanzapine-treated patients) were somnolence, asthenia, agitation, headache, nervousness, insomnia, hostility, paranoid reaction, rhinitis, constipation, dizziness, anxiety and bodyweight gain. However, ...
The goal of this study was to compare the efficacy and safety of olanzapine versus haloperidol in the treatment of agitation and aggression in patients with dementia. The subjects were 58 out-patients with dementia and agitation. After baseline assessments and, if necessary, a period of wash-out...
Elderly patients withdementia insomnia, dry mouth, orthostatic hypotension, tremor, and weight gain. Several disorders of movement also may occur with olanzapine, for example, extrapyramidal effects (sudden, often jerky, involuntary motions of the head, neck, arms, body, or eyes).Tardive dyskinesia...
Olanzapine is commonly used in elderly patients to control behavioral disturbances associated with dementia, delirium, and other psychiatric disorders. Leukocytoclastic vasculitis is an infrequently reported adverse drug reaction with olanzapine. Its exact pathogenic mechanism is unknown, but both cell-...
Antipsychotic agents, including olanzapine, are not approved for the treatment of dementia-related psychosis.IntroductionThienobenzodiazepine-derivative; atypical or second-generation antipsychotic agent. The drug is structurally similar to clozapine.Uses...