Therapy is initiated with 5-10 mg/day, and the dose may be increased by 5 mg a day at weekly intervals. The maximum dose is 20 mg daily. The recommended dose of extended release injection is 150-405 mg every 2 or 4 weeks. Treatment of bipolar disorder usually is initiated with oral ...
Increase dosage according to patient response and tolerance as indicated to a target dosage of olanzapine 6–12 mg with fluoxetine 25–50 mg daily.If elect to use combined olanzapine and fluoxetine therapy for extended periods, periodically reevaluate the long-term risks and benefits for the ...
83–85 In a recent multicenter randomized phase III trial, olanzapine (10 mg daily × 4) versus placebo was added to an antiemetic combination of a 5-HT3 inhibitor, aprepitant (or fosaprepitant), and dexamethasone in patients receiving cisplatin-based chemotherapy or cyclophosphamide-doxorubicin....
Oral olanzapine should be administered in combination with fluoxetine once daily in the evening, without regard to meals, generally beginning with 2.5 mgof oral olanzapine and 20 mg of fluoxetine. Dosage adjustments, if indicated, can be made according to efficacy and tolerability. Safety of co-ad...
Maternal doses of olanzapine up to 20 mg daily produce low levels in milk and undetectable levels in the serum of breastfed infants. In most cases, short-term side effects have not been reported, but sedation has occurred. Limited long-term follow-up of infants exposed to olanzapine indicates...
subsequent doses up to 10 mg may be given. However, the efficacy of repeated doses of intramuscular olanzapine for injection inagitated patients has not been systematically evaluated in controlled clinical trials. Also, the safety of total daily doses greater than 30 mg, or 10 mginjections give...
Bipolar I Disorder (manic or mixed episodes) in adolescents (2.2) Oral: Start at 2.5 to 5 mg once daily; Target: 10 mg/day Bipolar I Disorder (manic or mixed episodes) with lithium or valproate in adults (2.2) Oral: Start at 10 mg once daily Depressive Episodes associated with Bipolar...
We used a dose of 500 mg/kg (intraperitoneal, i.p.) D-Asp since we previously found that this con- centration elicited NMDAR-mediated signaling responses in vivo9. Remarkably, this treatment resulted in a rapid and robust increase of extracellular D-Asp levels in P < 0.0001; ...
(aged 9.6–16.3 years) treated with a mean dose of 4.13 mg daily of olanzapine. Significant improvements were seen in weight, functioning, ED symptoms, and hyperactivity. Similarly, Swenne and Rosling12reported 47 adolescents with AN treated with a mean dose of 5.1 mg daily. A mean weight ...
Her medications included clozapine 250 mg/day (50mg-0鈥 200mg-0), fluvoxamine 50mg once daily and olanzapine 20mg once daily. Two years prior to admission, she had been initiated on clozapine 250 mg/day. Fluvoxamine 25 mg/day had been started concomitantly, in orde ......