This manuscript addresses the role of O6-methylguanine-DNA methyltransferase (MGMT) as a biomarker in the oncogenesis of cancer and the opportunity of turning this gene into a drugable target in neuroendocrine tumours of the lung. Studies in brain tumours conclude that MGMT promoter methylation is ...
提供的O6-甲基鸟嘌呤-DNA-甲基转移酶MGMT(人源重组蛋白)(100 ug)产品形式为:50 mM Tris, pH 8.0, 150 mM sodium chloride, 10% glycerol 产品形式 O6-methylguanine-DNA Methyltransferase ��MGMT�� is a DNA repair enzyme responsible for demethylating O6-methylguanine ��O6-mG��. Th...
提供的O6-甲基鸟嘌呤-DNA-甲基转移酶MGMT(人源重组蛋白)(25 ug)产品形式为:50 mM Tris, pH 8.0, 150 mM sodium chloride, 10% glycerol产品形式 O6-methylguanine-DNA Methyltransferase ��MGMT�� is a DNA repair enzyme responsible for demethylating O6-methylguanine ��O6-mG��. The...
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. J Neurochem. 2006; 96 (3): 766-776.Hermisson M, Klumpp A, Wick W, et al: O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant...
上海玉博生物科技有限公司 主要致力于“Anti-MGMT (O6-methylguanine-DNA methyltransferase) O6甲基鸟嘌呤DNA甲基转移酶抗体 yb-1002R”的生产销售。多年的“Anti-MGMT (O6-methylguanine-DNA methyltransferase) O6甲基鸟嘌呤DNA甲基转移酶抗体 yb-1002R”生产与销售的
O6-Methylguanine-DNA methyltransferase and alkylation of liver DNA in mice exposed to dimethylnitrosamine during dietary deficiency of essential amino acids3MeA 3-methyladenine3-methyladenine7MeG N-7-methyl-guanineN-7-methyl-guanineO 6MeG O 6-methylguanine...
Sung Hak Lee, Suk Woo Nam, Yong Gil Hong, Chang Suk Kang, Youn Soo Lee. (2011) O6-methylguanine DNA methyltransferase gene promoter methylation status in glioblastoma and its correlation with other prognostic markers. Molecular & Cellular Toxicology 7 , 425-430 /...
FULL PAPER British Journal of Cancer (2015) 112, 523–531 | doi: 10.1038/bjc.2014.660 Keywords: O6-methylguanine-DNA methyltransferase; neuroendocrine tumours; alkylating agents; temozolomide; dacarbazine; streptozotocin O6-Methylguanine-DNA methyltransferase status in neuroendocrine tumours: prognostic ...
螖-O6-Methylguanine-DNA methyltransferase gene transfer for O6-benzylguanine and N,N'-bis(2-chloroethyl)-N-nitrosourea resistance, and use in protection of hematopoietic progenitors in chemotherapy.Gerson, Stanton LDavis, Brian MKoc, Omer N
The active methyltransferase and the methylated protein both have molecular weights of 21,000 to 22,000, as determined by gel filtration. Lymphoid cell lines proficient in repair of O6-methylguanine in vivo, Mex+, contain 10,000 to 25,000 molecules of the methyltransferase per cell. In ...