MGMT pr产品描述 提供的O6-甲基鸟嘌呤-DNA-甲基转移酶MGMT(人源重组蛋白)(25 ug)产品形式为:50 mM Tris, pH 8.0, 150 mM sodium chloride, 10% glycerol产品形式 O6-methylguanine-DNA Methyltransferase ��MGMT�� is a DNA repair enzyme responsible for demethylating O6-methylguanine ��O6-...
提供的O6-甲基鸟嘌呤-DNA-甲基转移酶MGMT(人源重组蛋白)(100 ug)产品形式为:50 mM Tris, pH 8.0, 150 mM sodium chloride, 10% glycerol 产品形式 O6-methylguanine-DNA Methyltransferase ��MGMT�� is a DNA repair enzyme responsible for demethylating O6-methylguanine ��O6-mG��. Th...
This manuscript addresses the role of O6-methylguanine-DNA methyltransferase (MGMT) as a biomarker in the oncogenesis of cancer and the opportunity of turning this gene into a drugable target in neuroendocrine tumours of the lung. Studies in brain tumours conclude that MGMT promoter methylation is ...
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. J Neurochem. 2006;96:766- 776.Hermisson M, Klumpp A, Wick W, Wischhusen J, Nagel G, Roos W, Kaina B and Weller M: O6‑methylguanine DNA meth- ...
MGMTMethylationPrognostic markersGlioblastoma is the most frequent and malignant brain tumor with most patients dying within 1 year after diagnosis. O 6 -Methylguanine DNA methyltransferase (MGMT) is implicated as a major predictive factor for treatment response to alkylating agents including temozolomide ...
1) O6-methylguanine-DNA-methyltransferase O~(6-)甲基鸟嘌呤-DNA-甲基转移酶2) O~6-methylguanine DNA methyltransferase MGMT基因(O~6-甲基鸟嘌呤-DNA甲基转移酶)3) O~6-methylguanine-DNA methyltransferase/ME O~6-甲基鸟嘌呤DNA甲基转移酶/代谢
6) O(6)-methylguanine-DNA methyltransferase O(6)-甲基鸟嘌呤DNA甲基转移酶补充资料:2-乙酰基-9-{[2-(乙酰氧基)乙氧基]甲基}鸟嘌呤 分子式:C12H15N5O5分子量:309.28CAS号:75128-73-3性质:暂无制备方法:暂无用途:开环鸟嘌呤(阿昔洛韦)的中间体。 说明:补充资料仅用于学习参考,请勿用于其它任何用途。
To assess the possible role of the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) in resistance of brain neoplasms to the clinically important chloroethylating agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), we quantitated MGMT activity, BCNU survival, and the effect of ...
O 6-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma. BBA Clinical. 2015;3:1-0.O 6 -methylguanine-DNA methyltransferase activity is associated with response to alkylating agent ...
Hoˆ pital Edouard Herriot, He´ patogastroente´ rologie, 69437 Lyon, France Background: O6-Methylguanine-DNA methyltransferase (MGMT) loss of expression has been suggested to be predictive of response to temozolomide in neuroendocrine tumours (NETs), but so far, only limited data are availa...