O-Alkylation in the Mitsunobu reaction of 2-pyridone, Tetrahedron Lett. 35 (1994) 2819e2822.Comins, D. L.; Jianhua, G. N- Vs O-Alkylation in the Mitsunobu Reaction of 2-Pyridone. Tetrahedron Lett. 1994, 35, 2819-2822.Comins et al. “N- vs. O-Alkylation in the Mitsunobu Reaction ...
Mechanistic studies implied key factors to slow down the undesired decomposition process of electrophiles in this reaction, which opened up the possibility of using secondary aliphatic alcohols as nucleophilic substrates. This asymmetric O-alkylation reaction proceeds under almost neutral conditions, tolerate...
ChemInform Abstract: Alkylation of Quinones by O-Silylated Ketene Acetals in LiClO4/Ether as Reaction Mediumalkylation, arylation, dealkylation, dearylation, C‐acylation, olefinationbenzofuran derivativesChemInform is a weekly Abstracting Service, delivering concise information at a glance that was ...
Fig. 3: Reaction condition optimization and the substrate scope of d2-alkyl TT salts in metallaphotoredox deuteroalkylation. a Optimizations of the reaction of aryl bromide 4a using TT salt 2a. b The scope of d2-TT salts coupled with aryl bromide 4a. Standard reaction conditions: aryl bromi...
g Alkylation of a mixture of 2 (0.35 mM) and 6 (0.34 mM) in 3 mL DMF. be isolated from this reaction. It appears that the formation of the hydroxy derivative 11 is facilitated by increasing the reactivity of the alkyl halide, since allyl bromide, and allyl chloride, respectively, yield...
Photoredox nickel catalysis has emerged as a powerful strategy for cross-coupling reactions. Although the involvement of paramagnetic Ni(I)/Ni(III) species as active intermediates in the catalytic cycle has been proposed, a thorough spectroscopic investi
3 | Reaction condition optimization and the substrate scope of d2-alkyl TT salts in metallaphotoredox deuteroalkylation. a Optimizations of the reaction of aryl bromide 4a using TT salt 2a. b The scope of d2-TT salts coupled with aryl bromide 4a. Standard reaction conditions: aryl bromide ...
An Unusual N-Alkylation Reaction During the Oxidative Addition of Hexafluoroacetone and Tetrachloro-o-benzoquinone to P-Bis(2-chloroethyl) amino-Substituted l3P-Compounds[J].Synthesis-Stuttgart,1996,(04):473-474.Neda I,Melnicky C,Vollbrecht A,Schmutzler R. An Unusual N-Alkylation Reaction During ...
Recently, Balskus and co-workers unveiled a biological C-alkylation involved in the biosynthesis of cyclophane natural products in cyanobacteria12. This reaction requires the previous stereoselective chlorination of an unactivated carbon center by the CylC halogenase. To create the final cyclophane dimeric...
1) O-alkylation 氧烷基化 2) alkoxylation 烷氧基化 1. Synthesis of 2-chloro-3-alkyl-5,6-dimethylpyrazine and itsalkoxylationand alkylthiolation; 2-氯-3-烃基-5,6-二甲基吡嗪的合成及其烷氧基化和烷硫基化反应 2. Experiments onalkoxylationof α-pinene with C 1-C 4 alcohols catalyzed by dea...