This transport process is accomplished by a family of transmembrane proteins called nucleotide sugar transporters (NSTs) [1]. The solute carrier family of human NSTs are designated as SLC35 (as per HGNC). Table 1 highlights the predominant members of this family and their key characteristics, ...
2.0 A4 appears to be a unique nucleotide sugar transporter with nine transmembrane domains and the N-terminus facing the Golgi lumen (Fig. 2S). This prediction is of very high probability (i.e. in the range 0.8–1.0). To additionally verify this bioinformatics score we employed five more ...
The products of these cDNAs are mutually related hydrophobic proteins consisting of 320-400 amino acid residues with multiple putative transmembrane helix domains, and are located in the Golgi apparatus. This review briefly summarizes the present status of the field of nucleotide sugar transporter ...
nucleotide sugar transportersEamAEmrEmulti drug resistance proteindual-topology proteinstransmembrane helixp pBackground/p pThe drug/metabolite transporter superfamily comprises a diversity of protein domain families with multiple functions including transport of nucleotide sugars. Drug/metabolite transporter ...
et al. Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human. Nat. Med. 13, 1363–1367 (2007). Article CAS PubMed Google Scholar Stanley, P. Golgi glycosylation. Cold Spring Harb. Perspect. Biol. 3, a00...
was recently reported in its substrate free and nucleotide sugar bound states10. This was recently followed by structures of both the mouse and maize CMP-sialic acid transporters11,12. These structures reveal a conserved architecture for the SLC35 family consisting of 10 transmembrane helices arranged...
DNA transmembrane transporter activity, protein-DNA-RNA complex, protein-DNA complex, DNA import into cell involved in transformation. Synsys ynno/i polynucleotide, nucleotides. Molekulen (polymer) yw TDN po DNA, hemm yw trenken dhioksiribonukleyek, a gomprehend kedhlow eritys pub tra byw, ...
TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE...
Structure and function of the uhp genes for the sugar phosphate transport system in Escherichia coli and Salmonella typhimurium. The nucleotide sequence of the uhp region cloned from Salmonella typhimurium was determined. The deduced Uhp polypeptide sequences from the two organisms are... MD Island,...
Eukaryotic Transmembrane Solute Transport Systems Milton H.SaierJr., inInternational Review of Cytology, 1999 9Nucleotide–Sugar Transporter Family (TC No. 2.51) Proteins of the NST family are found in theGolgi apparatusand the ER of eukaryotic cells (Abeijonet al, 1996, 1997; Berninsoneet al....