We have cloned a gene encoding one of these proteins ( NUP1) and have confirmed the localization of the NUP1 protein to the pore complex by immunofluorescence, using an epitope-tagged construct to differentiate it from other members of this family. The NUP1 protein is essential for cell ...
The nuclear pore complex (NPC) is a macromolecular protein assembly embedded in the double lipid bilayer of the nuclear membrane, and is the sole gateway of macromolecular traffic between the nucleus and cytoplasm. The NPC serves as a barrier to inhibit the free molecular flux in and out of ...
Nuclear pore complex protein Nup98 (315-360) 是核孔复合物 (NPC) 蛋白的 315-360 片段部分。 公司简介 武汉科斯坦生物科技有限公司是一家致力于前沿生物技术研发与成果转化的创新型高科技企业。 公司成立以来,一直专注于生命科学研发与技术服务领域,与 高校建立合作关系,逐步建立并完善了“分离纯化平台”、“分析...
et al. Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p. EMBO J. 18, 4332–4347 (1999). CAS PubMed PubMed Central Google Scholar Stelter, P. et al. Molecular basis for ...
中文名称:核孔复合体蛋白抗体,Anti-NUP107/Nuclear Pore Complex Proteins 英文名称:Anti-NUP107/Nuclear Pore Complex Proteins 别名: 107 kDa nucleoporin; NPC proteins; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP 107; NUP 84; NUP107; NUP153; NUP15...
[53]. The C terminal FG domain is highly flexible and interacts with nuclear transport receptors, indicating its role in NCT [54]. Nup153 also binds to the nuclear lamina and Sun1 protein [61] of the LINC complex. Depletion of either Nup153 or lamin leads to NPC clustering, suggesting ...
(NTF2)–related export protein-1, Nxf1: Nxt1 heterodimer, a nuclear export receptor [40]. Nxf1 has RNA recognition motif (RRM), leucine-rich repeat (LRR), and NTF2-like domain (NTF2L) arranged in this order from the N-terminal. There is a ubiquitin-associated–like domain (UBAL) ...
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm. Cell 72, 29–38 (1993). Article CAS PubMed Google Scholar Powers, M. A., Forbes, D. J., Dahlberg, J. E. & Lund, E. The vertebrate GLFG nucleoporin, Nup98, is an essential ...
[Deguelin regulates cell cycle and nuclear pore complex protein Nup98 and Nup88 in U937 cells in vitro]. Deguelin regulates cell cycle and nuclear pore complex protein Nup98 and Nup88 in U937 cells in vitro]. Chen Yan,Liu Hong-Li,Cui Guo-Hui,Wu Qiu-... Y Chen,H Liu,G Cui,... -...
The Nuclear Pore Complex (NPC) has emerged as an important hub for processing various types of DNA damage. Here, we uncover that fusing a DNA binding domain to the NPC basket protein Nup1 reduces telomere relocalization to nuclear pores early after telom