将新生的hIL3-hCSF2-Tg(M-NSG)小鼠进行亚致死计量辐照清髓,尾静脉注射脐血来源的CD34阳性的HSC细胞(1E5),并在注射后3-24周取血进行流式分析。 Fig5. Body weight growth curve and GvHD scores of huPBMC-M-NSG-hIL4 mice. 结果显示:huHSC-hIL3-hCSF2-Tg(M-NSG)小鼠呈现出良好的免疫重建效果,髓系细...
Fig 1. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(NMG) mice. Fig 2. Body weight growth curve of huPBMC-B2m-KO(NMG) mice. Fig 3. Survival rate of huPBMC-B2m-KO(NMG) mice. ...
Expectedly, we observed ruffling of the fur and significant body weight drops (Fig. 4A) in hACE2KIhomo-NSG mice at each timepoint compared to WT-NSG mice, which indicated that the method for establishing physiologically expressing mouse knock-in mice lines in the NSG background was successful...
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Next, to launch a CRS mouse model, FT-CAR T cells were administered into NSG-SGM3 mice engrafted with Nalm-6 cells. Mice received 1x107 FT-CAR or activated T cells intravenously. Health condition assessment and body index calculation were regularly monitored using weight, and body temperature...
Human,Mouse,Rat 已发表种属 Not Applicable 宿主/亚型 Rabbit / IgG 分类 Polyclonal 类型 Antibody 抗原 Synthetic peptide corresponding to amino acids 130-180 of human NEEP21 查看免疫原 偶联物 Unconjugated 形式 Liquid 浓度 1 mg/mL 纯化类型
However, since many investigators still use nude mice to study breast cancer growth and progression, we directly compared the nude to the NSG mouse model in both orthotopic and experimental metastasis (intracardiac) models. In the present study, we exam- ined the growth an...
Objective Choose the appropriate mouse model, evaluate BCMA-CAR-T anti-tumor effects, and explore the application of RNAscope in CAR-T cell therapy. Methods MM. 1s-luc multiple myeloma mouse model was established in NSG mice with severe immunodeficiency, they were randomly divided into extracellul...
The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as HIV-1 and to investigate multiple aspects of human immune system development. However, mouse and
Fig 1. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(NMG) mice. Fig 2. Body weight growth curve of huPBMC-B2m-KO(NMG) mice. Fig 3. Survival rate of huPBMC-B2m-KO(NMG) mice. ...