NSCLC diagnosis was determined through ICD9/10 codes. NGS tests ordered were limited to xT/xR (solid tumor DNA and RNA), xE (solid tumor whole exome), or xF (circulating tumor DNA). Aggregate unique patients with orders were summated on a per site basis. Descriptive statistics were used ...
16. Ost DE, Jim Yeung SC, Tanoue LT, Gould MK. Clinical and organizational factors in the initial evaluation of patients with lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based...
Patients with ALK-LC were identified according to crizotinib prescriptions (dispensed after an approved CHS' pre-authorization for an ALK-LC diagnosis). VTE was identified by ICD diagnosis codes 415.xx, 444.xx, 451.xx and 453.xx. VTE risk factors (Khorana score) were also extracted. Associati...
The initial metastasis sites were the brain (n = 10), bone (n = 6), lymph nodes (n = 6), intrathoracic organs (n = 5), and multiple organs (n = 17). At the time of diagnosis, 22 patients (50%) had combined brain metastasis. The initial mutations were in the EGFR (n = 32...
(K) In vitro methyltransferase assay, with the recombinant KMT5A protein incubated with the recombinant GST, GST-CD147ICD, or GST-CD147ICD-K234R proteins in methyltransferase buffer containing the methyl donor SAM. The di-methylation of CD147 was detected by an anti-CD147-K234me2 antibody. ...
During 2018, Medicare Advantage pts having 鈮 1 claim with diagnosis (dx) of lung cancer (ICD-10 C34), advanced disease (C77-C79), a PD-L1 test (CPT 88360) and test result, Tumor Proportion Score (TPS), were included. Pts were newly diagnosed (no C34 in 2017) and continuously ...
Surgery remains the main treatment for early-stage NSCLC (stages I and II, and some IIIA diseases), and approximately 30% of NSCLC patients present with the surgically resectable disease at initial diagnosis [5]; however, the risk of disease recurrence and cancer-related mortality are high, ...
2.2. Data Extraction and Handling Variables retrieved from the NCR included sex, age at diagnosis, morphology code (ICD-O 3rd edition), type of first-line treatment (categories including chemotherapy, radio- therapy, surgery, targeted therapy, other therapy, a combination of these, or no therapy...