2022年3月24日,华中科技大学附属同济医院肿瘤科褚倩教授为通讯作者,在顶尖期刊《Signal Transduction and Targeted Therapy》(IF值为38.104分)上发表题为“Notch signaling pathway: architecture, disease, and therapeutics”的综述性文章,详细阐述了Notch 信号的研究历史及在生理、病理状态下的调控机制。下面笔者将综述全...
2024年5月27日,浙江大学医学院附属第一医院李兰娟院士、朱丹华博士等在Signal Transduction and Targeted Therapy期刊发表了题为:Notch signaling pathway in cancer: from mechanistic insights to targeted therapies的研究论文。 该综述重点介绍Notch信号通路在癌症中的研究进展,深入探讨癌症发生和进展过程中Notch信号通路调...
因此,全面了解这些生物过程对于开发靶向Notch信号通路的创新治疗策略至关重要。 2024年5月27日,浙江大学医学院附属第一医院李兰娟院士、朱丹华博士等在Signal Transduction and Targeted Therapy期刊发表了题为:Notch signaling pathway in cancer: from mechanistic insights to targeted therapies 的研究论文。 该综述重点介...
2024年5月27日,浙江大学医学院附属第一医院李兰娟院士、朱丹华博士等在 Signal Transduction and Targeted Therapy 期刊发表了题为:Notch signaling pathway in cancer: from mechanistic insights to targeted therapies 的研究论文。 该综述重点介绍Notch信号通路在癌症中的研究进展,深入探讨癌症发生和进展过程中Notch信号通...
Notch signaling pathway: architecture, disease, and therapeutics. Signal Transduct Target Ther, 7 (1...
[1]Zhou B H, Lin W L, Long Y L, et al. Notch signaling pathway: architecture, disease, and therapeutics[J]. Signal Transduct Target Ther, 2022, 7(1): 95. [2]王雪淞, 周林, 李林材, 等. Notch信号通路调控间充质干细胞的增殖与分...
2024年5月27日,浙江大学医学院附属第一医院李兰娟院士、朱丹华博士等在 Signal Transduction and Targeted Therapy期刊发表了题为:Notch signaling pathway in cancer: from mechanistic insights to targeted therapies的研究论文。该综述重点介绍Notch信号通路在癌症中的研究进展,深入探讨癌症发生和进展过程中Notch信号通路...
Extensive research has been conducted on Notch signaling pathway, investigating its role as an oncogene or tumor suppressor in various cellular contexts. The involvement of the Notch signaling pathway in human malignancies was initially elucidated in T cell acute lymphoblastic leukemia (T-ALL), where ...
in advanced solid tumors and blood malignancies.Journal of Clinical Oncology 36, no 15_suppl.3. Naoko Takebe, et al. Targeting notch signaling pathway in cancer: clinical development advances and challenges. Pharmacol Ther. 2014 Feb;141(2):140-9.4. Li Yi, et al. Notch1 signaling pathway ...