(2015) Targeting human long noncoding transcripts by endoribonuclease-prepared siRNAs. J. Biomol. Screen. 20, 1018-1026Surendranath, V., Theis, M., Habermann, B.H., and Buchholz, F. (2013). Designing efficient
sense strand;antisense strand;antisense exonic;noncoding transcripts; 答案 sense strand是指编码链 不作为转录 的另一条DNA链为编码链,又称有意义链.antisense strand是指反义链 在基因的DNA双链中,转录时作为mRNA合成模板的那条 DNA单链叫做模板链或反义链.还有的两个就不知道了.相关推荐 1sense strand;anti...
Long noncoding transcripts can be defined by their location relative to nearby protein-coding genes [10]. Long noncoding natural antisense transcripts (lncNATs) initiate inside or 3 0 to a protein-coding gene, are transcribed in its
. LncRNA transcripts are modular assemblages of functional elements that can interact with other nucleic acids and proteins via defined sequences or structural elements23,24. Of the >50,000 loci mapped in the human genome25, hundreds of “cancer-lncRNAs” have been demonstrated to act as ...
Microarray and RNA sequencing (RNAseq) technologies have revealed novel alternative protein-coding and noncoding transcripts not included in RNA references databases and therefore previously overlooked in the study of androgen-responsive genes in prostate cancer. Newly described unconventional roles for RNA...
We employed several criteria to identify noncoding transcripts. First, possible partial sequence reads and artificial sequencing reads were removed based on FPKM values. Only the transcripts with an FPKM value more than 0.1 were retained. We then selected transcripts that had not been annotated in ...
plant long noncoding RNAsRNA‐related methodologiestranscriptional read‐throughtranscriptionThe extraordinary maturation in high‐throughput sequencing technologies has revealed the existence of a complex network of transcripts in eukaryotic organisms, including thousands of long noncoding (lnc) RNAs with ...
Previously, two characterized R-loops in Arabidopsis uncovered the action in cis of noncoding transcripts, involved in transcriptional self-repression or alternative splicing, respectively (Sun et al., 2013, Conn et al., 2017). Our findings challenge the concept of a distance-based restriction for...
[3]. The DNA molecules that make up the human genome are about 3 billion base pairs, of which about 5–10% are stably transcribed, but protein-coding genes account for less than 2% of the human genome. The remaining 3–8% of the genome are transcribed into non-coding transcripts, i....
NoncodingRNA非编码RNA Repertor:XiaoningYuan Oct.9.2012 Page1 Irnne.MP,ChengG,Wieland.S,etal，2007 NoncodingRNA IntroductionClassificationResearchmethodMechanismTherelationshipwithmajordisease 1.Introduction NoncodingRNA(ncRNA)isakindoftranscriptswithouttheabilityofcodingproteins,which...