NAFLD and nonalcoholic steatohepatitis (NASH) represent the hepatic manifestation of "metabolic syndrome." NAFLD-related cirrhosis is becoming the most common cause of cirrhosis, a cause of primary hepatocellular carcinoma, and rarely intra-hepatic cholangiocarcinoma. The prevalence of NAFLD after age 75...
Metabolic dysfunction-associated steatohepatitis (MASH): This used to be known as nonalcoholic steatohepatitis (NASH). It's the advanced stage of FLD and means you have inflammation in your liver. The inflammation and liver cell damage that happen with MASH can cause serious problems such as hepa...
Development of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) after pancreaticoduodenectomy: proposal of a postoperative ... We explored the clinical characteristics of newly appearing nonalcoholic fatty liver disease (NAFLD) after pancreaticoduodenectomy (PD), designated...
lipid, and amino acid metabolism. An imbalance of hepatic metabolic homeostasis will lead to liver diseases. A common chronic liver disease is non-alcoholic fatty liver disease (NAFLD), which ranges from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH). NASH is characterize...
Nonalcoholic steatohepatitis (NASH), as a severe form of nonalcoholic fatty liver disease (NAFLD), is characterized by liver steatosis, inflammation, hepatocellular injury and different degrees of fibrosis. The pathogenesis of NASH is complex and multifa
Exclusion criteria included influential general conditions (e.g. renal failure or heart failure), other liver diseases, any medical histories known to cause steatosis and/or steatohepatitis, and alcohol intake 5 g/day. NAFLD patients aged Outcome measures The primary outcome measures were ...
α-SMA α-smooth muscle actin, CVF collagen volume fraction, DSF disulfiram, Fxr−/− farnesoid X receptor knockout, H&E hematoxylin and eosin, NAS NAFLD activity score, NASH nonalcoholic steatohepatitis, ORO oil red O, TG triglyceride, WT wild-type. Source data are provided as a Source...
NAFLD: Non-Alcoholic Fatty Liver Disease NASH: Nonalcoholic Steatohepatitis NOS: Newcastle–Ottawa Scale PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses PROSPERO: International Prospective Register of Systematic Reviews SD: Standard Deviation sROC: Summary Receiver Operating...
NAFLD, which also encompasses the more serious nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma2,3,4. The development of NAFLD is a complex process determined by both environmental cofactors and genetic predisposition, and is strongly associated with obesity, insulin resistance...
Pediatric fatty liver disease often displays a histologic pattern distinct from that found in adults, and liver biopsy remains the gold standard for diagnosis of nonalcoholic steatohepatitis (NASH). Lifestyle modifications that result in weight loss remain the first-line treatment of NAFLD in children...