We utilized a breeding strategy with C.B-17scid/scid (SCID) (H-2(d)) mice and SJL (H-2(s)) mice to generate immunodeficient mice that were histocompatible with the inbred SJL strain (H-2(s)) in order to evaluate the role of histocompatible recipient lymphocytes in adoptively...
The primary MCs disappeared after complete resorption of the FBs, indicating that the MCs could not grow without human FBs in the CB17/SCID mice. More recently, a new SCID strain, nonobese and diabetes-free (NOD)/LtSz-scid/scid (NOD/SCID) mice, are known to be the most immunodeficient...
While under anesthesia, 10 2.6 plaque forming units (pfu) of salivary gland passaged, Smith strain MCMV was injected in the anterior chamber of 6- to 8-week-old severe combined immunodeficiency (SCID) mice. At various times post-inoculation, bright-flash scotopic electroretinogram, viral titer...
SCID-repopu- lating activity of human umbilical cord blood-derived hematopoi- etic stem and/or progenitor cells in a nonobese diabetic/Shi-SCID mice serial xenotransplantation model and immune cell activities in vitro: a comparative study of the filter method and the hydroxy- ethyl starch method...
Purpose:This study is to evaluate the feasibility of dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) in subcutaneously transplanted vascularendothelial growth factor (VEGF) overexpressing NSCLC in a severe combined immunodeficiency (SCID) mice model.Introduction:VEGF is an endotheli...
Spontaneous nonthymic tumors in SCID mice. Comparative medicine. 2011; 61(3):227-34. PMID: 21819692; PubMed Central PMCID: PMC3123755.Huang P, Westmoreland SV, Jain RK, et al. Spontaneous non- thymic tumors in SCID mice. Comp Med 2011; 61: 227-234....
The invention provides a method for establishing a xenogeneic graft-versus-host disease model for NOD/SCID (non-obese diabetic/severe combined immunodeficient) mice, which includes: preparing active human PBMCs (peripheral blood mononuclear cells), establishing a model of NOD/SCID mice, detecting ...
N-acetyl-cysteine accelerates transfer of diabetes into non-obese diabetic scid mice Diabetologia. 2004;(10):1803-9.Irie J, Shimada A, Oikawa Y, Shigihara T, Saruta T: N-acetyl-cysteine accelerates transfer of diabetes into non-obese diabetic scid mice. Diabe- tologia 47:1803-1809, 2004...
Mosier DE, Gulizia RJ, MacIsaac PD, Torbett BE, Levy JA: Rapid loss of CD4 + T cells in human-PBL-SCID mice by noncytopathic HIV isolates. Science 260:689–692, 1993Mosier DE, Gulizia RJ, MacIsaac PD, Torbett BE, Levi JA. Rapid loss of CD+ T cells in human-PBL- SCID mice by ...
We found that EBC-1, a human non-small cell lung cancer (NSCLC) cell line, formed multiple metastases in the lung after subcutaneous inoculation into severe combined immunodeficiency (SCID) mice. SCID mice were injected in the flank with 10 6 EBC-1 cells. Metastases in the lung were ...