CNS (conserved non-coding sequences)doi:10.1007/978-1-4020-6754-9_3215non-coding sequencesSpringer NetherlandsEncyclopedia of Genetics Genomics Proteomics & Informatics
Comparative genomics approaches have identified numerous conserved cis-regulatory sequences near genes in plant genomes. Despite the identification of these conserved noncoding sequences (CNSs), our knowledge of their functional importance and selection remains limited. Here, we used a combination of DNA...
At least 17.7% of the assembledA. thalianagenome sequence (21.1 Mb) seemed to be evolving under constraint (Fig. 3a), with close to a quarter of this sequence (4.5 Mb) located outside of protein-coding regions. In the larger TE-richA. lyratagenome, very slightly more sites seemed to be...
KaKs_Calculator 3.0 is an updated toolkit that is capable of calculating selective pressure on both coding and non-coding sequences.Similar to the nonsynonymous/synonymous substitution rate ratio for coding sequences,selection on non-coding sequences can be quantified as the ratio of non-coding nucl...
‘Default’ generated neonatal regulatory T cells are hypomethylated at conserved non-coding sequence 2 and promote long-term cardiac allograft survival19阅读 文档大小:893.97K 13页 ppirvo29上传于2015-12-12 格式:PDF the function of regulatory t cells at the ocular surface review.[2017][ocul surf...
Non-coding sequences, once thought to be transcriptionally inert, have been shown to be actively transcribed into a large variety of non-coding RNAs. They are now the object of intensive research due to their ability to participate in the regulation of nuclear structure and gene expression (Bon...
VarMap: a web tool for mapping genomic coordinates to protein sequence and structure and retrieving protein structural annotations 资料: Variant effects on protein structure | EMBL-EBI Train online Predicting the effect of variation on protein structure and function ...
Therefore, accurate sequence-based prediction of chromatin features requires a flexible quantitative model capable of modeling such complex dependencies—and those predictions may then be used to estimate functional effects of noncoding variants.基于序列的,可以考虑到更多复杂的情况,这比单纯的依赖现有的motif...
(CNCI), by profiling adjoining nucleotide triplets to effectively distinguish protein-coding and non-coding sequences independent of known annotations. CNCI is effective for classifying incomplete transcripts and sense-antisense pairs. The implementation of CNCI offered highly accurate classification of ...
The region immediately upstream of the first AUG sequence in a long intergenic non-coding RNA. Tau score A rank correlation coefficient used to conduct a non-parametric hypothesis test for the statistical correlation between data variables. Nuclear paraspeckles Mammalian nuclear organelles, the formation...