There has been a change in the management of patients with localized cancer from total mastectomy to lumpectomy complemented by adjuvant radiotherapy and chemo-endocrine therapy, without significant outcome. Early detection of small breast carcinoma lesions may further change the attitude toward less ...
New paradigm of non-toxic cancer treatment. World leaders in DCA therapy and metabolic cancer therapy. Medical ozone therapy.
Bladder cancer (BC) is a common malignancy with a high morbidity and mortality rate. There are two different subtypes of bladder cancer: non-muscle-invasive bladder cancer and muscle-invasive bladder cancer. The primary treatment for non-muscle invasive bladder cancer is TURBT, y...
Chemotherapy is proved to be the standard first-line treatment for various cancers, while the therapy-resistance mediating by lncRNAs usually results in poor prognosis. In bladder cancer, for example, lncRNAs can inhibit apoptosis and promote proliferation. Urothelial cancer-associated 1 (UCA1) has b...
TWIST1 is a prognostic factor for neoadjuvant chemotherapy for patients with resectable pancreatic cancer: a preliminary study Recent advances in the development of chemotherapies have helped improve the prognosis of pancreatic ductal adenocarcinoma (PDAC). However, predicting fact... S Fujiwara,Y Saiki...
Circulating cancer biomarkers: the macro-revolution of the micro-RNA. EBioMedicine 2016; 5: 4–6. Article PubMed PubMed Central Google Scholar Casey MC, Sweeney KJ, Brown JA, Kerin MJ . Exploring circulating micro-RNA in the neoadjuvant treatment of breast cancer. Int J Cancer 2016; 139:...
Radiotherapy is an adjuvant treatment of surgery in prostate cancer, while radioresistance has been the challenge of treatment. It has been reported that α-Solanine exhibits anti-cancer activity and enhances the chemo- and radio-sensitivity in several human cancers, whereas the role of α-Solanine...
Our clinical studies discovered that high Rac1 expression was correlated with poor outcome to neoadjuvant treatment in the breast cancer patients (Fig. 1j, k, Supplementary Table 3). Importantly, ROC curve showed that high Rac1 level significantly distinguished chemoresistant cases from sensitive ...
Breast, cervical and colorectal cancers are the three most frequent cancers in women, while lung, prostate and colorectal cancers are the most frequent in men. Much attention has been given to the economic evaluation of pharmaceuticals for treatment of cancer by the National Institute for Health an...
141 Phenotypic switching has important implications for treatment, as most radiation and chemotherapies target highly proliferative cells and, as such, are much less effective against DTCs with mesenchymal stem-like traits, which are primed to enter a slow-cycling state and ultimately seed lethal ...