It is easy to think of chemo as the enemy, but it really should be thought of as an ally. It is used to fight the enemy. Any cancer diagnosis is not fun but by gaining a clear understanding of what treatment does and how it relates to you gives one a fighting edge and a fighting...
doi:10.1016/j.ejcsup.2008.06.025S. BarniM. CabidduF. PetrelliElsevier LtdEJC SupplementsS.Barni, M.Cabiddu, F.Petrelli. (2008) Chemo-hormonal therapy for metastatic breast cancer patients: Treatment strategy. European Journal of Cancer Supplements 6 , 13-20 /...
Chemotherapy is a medical treatment that is used to treat cancer using anti-cancer drugs. The drugs administered inhibit mitosis, or cell division of the cancer cells. One of the side affects is often hair loss, because the drugs usually also impact normal, healthy, fast-dividing cells, such...
Metaplastic breast cancer is a highly chemoresistant breast cancer subtype with limited therapeutic options. Here, the authors report that the NOS inhibitor, L-NMMA, sensitises metaplastic breast cancer to a selective PI3K inhibitor, alpelisib, and taxane chemotherapy via repression of c-JUN mediated...
Cardiac adverse events such as decreased ejection fraction and heart failure have been of particular concern in patients with HER2+ breast cancer. Anti-HER2 agents and chemotherapies (specifically anthracyclines, which are frequently used to treat HER2+ disease) have been associated with ...
Breathlessness, however, was shown to increase the likelihood of the oncologist recommending chemo- therapy. This factor relates to the goal of symptom relief which was viewed as an achievable goal of chemotherapy by the clini- cians. The present study elicited important information regarding ...
Home to the journal Oncology, Cancer Network provides research and opinion on the screening, early detection, diagnosis, treatment, and prevention of cancers.
drug resistance is common in all breast cancer types despite the different treatment modalities applied. The development of resistance to different therapeutics is not mutually exclusive. It seems that tumor could be resistant to multiple treatment strategies, such as being both chemoresistant and monocl...
cancers3,4,5. The design of novel therapy as well as optimal combination strategy require detailed understanding of the effects of chemotherapies on tumor cell intrinsic biology as well as tumor microenvironment. To date, the tumor associated immunomodulatory effects and mechanisms of chemotherapeutic ...
Objective To compare time to cancer treatment initiation and relative dose intensity (RDI) of neoadjuvant and adjuvant chemotherapy among patients with breast cancer with vs without HIV. Design, Setting, and Participants A retrospective, matched cohort study enrolled women who received a diagnos...