The method of choosing chemotherapy for treatment of patients with breast cancer includes immunohistochemical investigation of 5 markers: for the estrogen receptors (ER), progesterone (ER), epidermal growth factor HER2-neu, Ki-67 and p53. Additionally, three more markers are determined: BCRP, MRP1...
[Oncotype DX. Treating breast cancer with or without chemotherapy. Deciding which is best] [Article in French] Marie-Michèle Mantha - 《Perspective Infirmière Revue Officielle De Lordre Des Infirmières Et Infirmiers Du Québec》 被引量: 1发表: 2012年 CATHEPSIN-D AND ANGIOGENESIS INHIBITORS AND...
Jager noted that although the largest study of its kind, the number of men with breast cancer was still small and data were lacking on the extent of advanced disease, BRAC mutation status and type of chemotherapy. However, she said: "More detailed information and longer-term follow-up will ...
Breast-cancer-related lymphedema (BCRL) is a common consequence of oncological treatment. Its management is a complicated, chronic, and arduous process. Th
In the phase 2 SOLTI VALENTINE trial, patritumab deruxtecan with or without letrozole showed similar efficacy to multiagent chemotherapy in HR-positive, HER2-negative breast cancer with fewer severe adverse events. Read More Ten-Year Retrospective Trial of Ponatinib in Leukemia Sheds Light on AE...
Blood stream cancers being one of the most difficult cancer types to treat, allogeneic stem cell transplantation with chemotherapy or radiotherapy was the conventional treatment process over the decades. Since most of hematologic malignancies caused by precursor B or T cells, T cell therapy using ...
In chemotherapy-naive patients with mCRPC in PREVAIL, treatment with enzalutamide was associated with significantly improved OS compared with placebo [52]. In the AFFIRM trial, enzalutamide also was associated with significantly prolonged post-chemotherapy OS versus placebo in patients with mCRPC [53]....
As described herein, phosphorylation at serine 319 of FOXO1 activates tumor suppressor functions of FOXO1 in inhibition of ERK activation, the Warburg effect, and chemotherapy resistance in cancer. Also as described herein, a 30 amino acid phosphorylation-mimicking peptide derived from a human FOXO1 ...
What if you could treat cancer without surgery, without chemotherapy and without ionizing radiation? What if you could extend a dying patient's life by years without any side effects? And if the patient were in pain, you could get rid of that too? All that may be possible sooner than y...
The three ongoing trials of chemotherapy have a total target accrual of nearly 2000 patients. Authors' conclusions This systematic review of randomised trials provides insufficient evidence to support systemic treatment in women with loco-regional recurrence of breast cancer. Participation in randomised ...