The invention provides a newly discovered oxadiazole class of antibiotics. The oxadiazoles impair cell-wall biosynthesis and exhibit activities against the Gram-positive bacteria such as the bacterium , including methicillin-resistant (MRSA) and vancomycin-resistant and linezolid-resistant . For example, ...
Davidovich C, Bashan A, Yonath A (2008) Structural basis for cross-resistance to ribosomal PTC antibiotics. Proc Natl Acad Sci USA 105:20665–20670 CrossRef De Carli L, Larizza L (1988) Griseofulvin. Mutat Res 195:91–126 CrossRef Debono M, Gordee RS (1994) Antibiotics that inhibit ...
Efficacy of Non-Beta-lactam Antibiotics for Prevention of Cesarean Delivery Surgical Site Infections Efficacy of Non-Beta-lactam Antibiotics for Prevention of Cesarean Delivery Surgical Site Infectionsantibiotics, penicillin allergy, cesarean delivery, surgical ... BS Harris,MK Hopkins,MS Villers,... -...
ChemInform Abstract: Total Synthesis of Non-Classical β-Lactam Antibiotics by the Ester Enolate-Imine Condensation Routeorganic chemistry, reviewantibioticsChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a...
ChemInform Abstract: Total Synthesis of Non-Classical β-Lactam Antibiotics by the Ester Enolate-Imine Condensation Routedoi:10.1002/chin.199134303organicchemistryreviewantibioticsChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading ...
3f). In addition, the non-antibiotic pharmaceuticals promoted the expression of ampC (Table S24), which is related to resistance towards β-lactam antibiotics [74]. We also found that the exposure of non-antibiotic pharmaceuticals caused large-scale changes in the expression of TonB-related ...
antibiotics (*J01RA), of which almost all were a combination of 3rd generation cephalosporins with β-lactamase inhibitors. Prescribing the combinations of cephalosporin with β-lactamse inhibitor are justified in cases of ESBL producing strains ofE. coliandKlebsiellaand thus to keep carbapenems as ...
Aquaculture is an important food source worldwide. The extensive use of antibiotics in intensive large-scale farms has resulted in resistance development. Non-intensive aquaculture is another aquatic feeding model that is conducive to ecological protecti
Herein, we describe the development of non-β-lactam-based potentiator molecules that synergize with β-lactam antibiotics and β-lactam-β-lactamase inhibitor combinations against MDR/XDR P. aeruginosa phenotypes. The compound comprises a chemical structure or chemical formula of Formula (A) or a ...
A non-synonymous polymorphism in galectin-3 lectin domain is associated with allergic reactions to beta-lactam antibiotics. Pharmacogenomics J 2015.Cornejo-Garcia, J.A.; Romano, A.; Gueant-Rodriguez, R.M.; Oussalah, A.; Blanca-Lopez, N.; Gaeta, F.; Tramoy, D.; Josse, T.; Dona, I...