Extended-spectrum 尾-lactamases (ESBLs) are defined as those bacterial enzymes which are capable to hydrolyze most beta-lactam antibiotics, including penicillins, cephalosporins, and the monobactam aztreonam and especially expanded spectrum cephalosporins such as ceftriaxone, ...
Antibiotics produce their effects through a variety of mechanisms of action. A large number work byinhibitingbacterialcell wallsynthesis; these agents are referred to generally as β-lactam antibiotics. Production of the bacterial cell wall involves the partial assembly of wall components inside the cel...
The potential neurotoxicity of betalactam antibiotics are well-known and is frequently associated with drug accumulation in patients with renal failure since these antibiotics are eliminated mostly by kidneys. The regional center of pharmacovigilance of Amiens has collected since 10 years, 20 notifications...
Beta-Lactams Penicillins Cephalosporins Macrolides Fluoroquinolones Tetracyclines Aminoglycosides Most commonly used types of antibiotics are: Aminoglycosides, Penicillins, Fluoroquinolones, Cephalosporins, Macrolides, and Tetracyclines. While each class is composed of multiple drugs, each drug is unique in some...
The extreme selectivity of some cellular components to recogn... M. T. Vilaró,M. I. Martinez-Mir,M. Sarasa,... - Macmillan Education UK 被引量: 12发表: 1991年 Beta-lactam antibiotics The large family of β-lactams comprises penicillins, cephalosporins, cephamycins, monobactams, carba...
The emergence of such strains resistant to all beta-lactam antibiotics available is of great concern because of the limitation of therapeutic choices for patients with invasive Salmonella infections. Over the study period resistance to fluoroquinolones tested was seen in 1.3% of the isolates, while ...
All over the world, strains of E faecium resistant to beta-lactam antibiotics and fluoroquinolones were noted, which can be explained by the clonal spread of isolates with a mutation in key genes for resistance, as well as the horizontal transfer of the mutated gene among the strains. The lit...
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Results: All strains were resistant to beta-lactam antibiotics, carbapenems, and quinolones. On the other hand, only nine (8.9%) strains were resistant to colistin. The most common carbapenemase genes were blaNDM (64.3%) and blaOXA-48 (53.5%). Besides, 28 (27.7%) strains were found to ...
A broad range of serotypes are responsible for Salmonellosis in Shenzhen, with Enteritidis and Typhimurium being the most common serotypes. The high level of antibiotic resistance is of public health significance and ongoing monitoring combined with rational use of antibiotics are recommended. Point mut...