NOD/scid Mice 类型: 小鼠类 价格: ￥260.00~290.00 单位: 只 周龄: 3-8周 性别: 雄性 雌性 品牌: 北京斯贝福 北京华阜康 购买数量: 加入购物车 立即购买 产品详情 起源:Scid小鼠是C.B-17小鼠的突变系,C.B-17小鼠是BALB/c小鼠的同源近交系,该小鼠除了 携带来自C57BL/Ka小鼠的免疫球蛋白...
Paralysis does seem to be a phenotype of NOD scid mice, however in measuring this phenotype in our colonies it is present in less than .5% Origin The NOD scid Spontaneous mutant model was developed by the Fox Chase Cancer Center by transferring the scid mutation from a C.B-17 congenic bac...
NOD背景导致小鼠NK细胞功能低下,补体和巨噬细胞活性降低,且NOD背景小鼠巨噬细胞表面的信号调节蛋白Sirpα,对人CD47具有高亲和力,利于人类细胞/组织的移植。SCID突变系导致T和B淋巴细胞功能缺失。 (左)IFN-g和LPS可刺激骨髓巨噬细胞的IL-1产生量,用以评估巨噬细胞的活性。 (右)通过小鼠血清中的51Cr评估补体依赖...
Disclosed herein is a non-obese diabetic (NOD) in the context of hairless, immunodeficient mice and its production process. 所述小鼠为无毛的,并且具有多重免疫缺陷,包括B细胞和T细胞缺陷,以及受损的巨噬细胞和补体功能. The hairless mice, and has multiple immune defects, including B cells and T ...
M-NSG 小鼠(NOD-PrkdcscidIl2rgem1/Smoc) 由南模生物自主研发,该品系在 NOD-SCID 的基础上敲除 Il2rg 基因,是一种严重免疫缺陷小鼠,缺失成熟T、B、NK细胞,是人源化小鼠、异种移植、免疫重建的重要载体;对于研究人类造血干细胞、肿瘤发生与治疗、免疫缺陷疾病与体内免疫机制研究都具有重要意义。
The NOD/SCID mice serve also as a preclinical model to study the phenotype of human leukemic stem cells, the SLICs, which mostly display a primitive, nondifferentiatedCD34+/CD38−expression profile. These cells extensively repopulate the BM of irradiated mice and initiate the disease similarly to...
to analyze the essential function of the E2F-1 molecule in the development of IDDM and SS; and the dysfunction of the pancreas islet and salivary gland in the NOD background using NOD/SCID mice. We produced NOD/SCID.E2f1(-/-) mice using homologous recombination; determined diabetes ...
NSG mouse strain is an immunodeficient mouse that knocks out the interleukin 2 receptor gamma chain (IL2Rγ) gene on the basis of NOD/SCID[77]. This mice strain lacks mature T and B lymphocytes and completely loses NK cell activity[78]. Compared with NOD/SCID mice, the transplantation ...
Product Name:NOD-SCID mice Synonyms:Nod scid mouse CAS: MF: MW:0 EINECS: Mol File:Mol File Browse by Nationality Suppliers>Global suppliers Guangdong (2)Member(2)All (2) Please select the suppliers Recommend You Select Member Companies ...
Glandular secretory epithelial cell apoptosis was elevated in both NOD and NOD-scid mice, however; there was little evidence of apoptosis in the control strain of BALB/c mice. CONCLUSION: These results suggest a potential apoptotic process dependent on Fas:FasL interactions occurring in NOD-scid ...