Get Print Copy of this Pathway View NOD-like Receptor Signaling Pathways Image Related Information NLRP10 Is Required for Dendritic Cell-mediated Initiation of the Adaptive Immune Response NOD-like Receptors and the Inflammasome Obesity-Induced Activation of the Nlrp3 Inflammasome Promotes Insulin Resistan...
细胞焦亡过程涉及多种炎症小体信号通路的激活,其中对NOD样受体家族Pyrin域蛋白(NOD-like receptors family Pyrin domain containing,NLRP)3炎症小体的研究较深入。目前,研究结果证实,NLRP3炎症小体诱导的细胞焦亡在骨髓增生异常综合征(myelodysplastic syndromes,MDS)发病中发挥重要作用[ 1 ]。但是细胞焦亡是否参与除MDS...
炎症小体包括多种亚型,其中NOD样受体蛋白3(nod-like receptor protein 3,NLRP3)亚型主要促进炎症反应。NLRP3炎症小体是一种多蛋白复合物,其活化可以上调炎症细胞因子的表达,还可以调节细胞自噬、死亡和纤维化等进程从而影响糖尿病并发症的发生和发展。本文对NLRP3炎症小体在调控糖尿病肾病(diabetic nephropathy,DN)、...
An overview of the NOD-like receptor signaling pathway, introduction, the regulation of pathway and clinical significance.
our approach provided more information about the transcriptional dysregulation in the epidermis. A good example is the recognition of the NOD-like receptor signaling and functions related to it, such as inflammasome activation in keratinocytes. The 5′-end RNAseq method allowed the precise determination...
NOD-likereceptorfamily,pyrindomaincontaining3(NLRP3)contributestoinflammation,pyroptosis,andmucinproductioninhumanairwayepitheliumonrhinovirusinfectionTaoLiu,PhD,a*YuTaoZhou,MD,b,c*LiQiuWang,BSc,a*LiYueLi,MD,b,c*QingBao,MD,b,cShuoTian,BSc,aMeiXinChen,PhD,aHeXinChen,MD,PhD,b,cJunCui,PhD,aandChun...
Platelet-rich plasma alleviates skin photoaging and oxidative stress in rats by regulating autophagy and inhibiting the NLRP 3 inflammasome pathway In addition, RPR activated autophagy to inhibit NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome signaling pathway-related ....
Xiao YT, Li GX, Wang XM. Effect mechanism of NOD like receptor signaling pathway on intestinal mucosal barrier of rat during early phase of acute intra-abdominal infection [J]. Chin Crit Care Med, ...
Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin1 in acute kidney disease. Acta Pharmacol Sin. 2021;43:86–95. Qian Y, Qian C, Xie K, Fan Q, Yan Y, Lu R, et al. P2X7 receptor signaling promotes inflammation in renal parenchymal cells suffering from ischemia...
近些年来有研究发现Toll样受体4(toll like receptor 4,TLR4)与Nod样受体蛋白3(nod-like receptor family pyrin domain-containing protein 3,NLRP3)炎性小体作为细胞炎症因子可以通过启动天然免疫,刺激相应的信号通路途径产生细胞因子和...