PRR主要有以下两类受体:一类是位于细胞膜表面或内体膜上的Toll样受体(Toll-like receptor,TLR),另一类是位于细胞质内的核苷酸结合寡聚化结构域(nucleotide- binding oligomerization domain,NOD)样受体及视黄酸诱导基因(retinoic acid induc...
An overview of the NOD-like receptor signaling pathway, introduction, the regulation of pathway and clinical significance.
Get Print Copy of this Pathway View NOD-like Receptor Signaling Pathways Image Related Information NLRP10 Is Required for Dendritic Cell-mediated Initiation of the Adaptive Immune Response NOD-like Receptors and the Inflammasome Obesity-Induced Activation of the Nlrp3 Inflammasome Promotes Insulin Resistan...
The results showed that the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) signaling pathway that was involved in immunity may play a crucial function in lung injury caused by plateau hypoxia. And the expressions of NOD1, NOD2, IL-1β, TNF-α, IL-6, and IL-18 were h...
[Key words] Nucleotide-binding oligomerization domain-like receptor; Signaling pathway; Tumor 先天性免疫应答是机体抗感染免疫的第 一道防线,相对于适应性免疫应答来说具有 出现早,应答发生速度快等特点.其主要识 别病原体相关分子模式(pathogen-associated molecular patterns,PAMPs)和损伤相关的分 子模式(damage-...
AMPK signaling pathway View more pathways>> All All Primary antibodies Secondary antibodies Peptides NOD-like receptor signaling pathway Specific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor...
The nod-like receptor(NLR) family :a tale of similarities and differences[J]. PLoS One, 2008, 3(4):e2119. [9]Bonardi V, Dangl JL. How complex are intracellular immune receptor signaling complexes?[J]. Frontiers in Plant Science, 2012, 3 : 237. [10]Correa RG, Milutinovic S, Reed...
NOD-like receptor signaling pathway activation: A potential mechanism underlying negative effects of benzo(α)pyrene on zebrafish - ScienceDirectYongzhan Mai aSongyao Peng aHaiyan Li aYuan Gao aZini Lai a b cComparative Biochemistry and Physiology Part C: Toxicology & Pharmacology...
factors through a variety of signaling pathways. This review presents the constitution of NOD-like receptor, NOD-mediated signaling pathways and the relationship between NOD-like receptor and tumors.［Key words ］ Nucleotide-binding oligomerization domain-like receptor; Signaling pathway; Tumor ...
our approach provided more information about the transcriptional dysregulation in the epidermis. A good example is the recognition of the NOD-like receptor signaling and functions related to it, such as inflammasome activation in keratinocytes. The 5′-end RNAseq method allowed the precise determination...