NK cells are a vital component of our innate immune system and serve a variety of biologic functions, including the eradication of tumor. Their importance in preventing leukemic relapse after stem cell transplantation is well documented. The cytotoxic activity of NK cells is regulated by activating ...
NK1.1表达的 4、诱导可以发生在胸腺, 但大部分从胸腺移出的细胞NK1.1为阴性, 表明NKT细胞的最终成熟阶段也可发生在外周血。3 NKT细胞的分型 目前所指的NKT细胞均为CD1d限制性, 根据TCR (小鼠V14J18, 人类V24J18) 的表达与否, 而将NKT细胞分为V14J18+型NKT细胞和V14J18NKT细胞, 通常所说的NKT细胞即为型NKT...
Invariant natural killer T (iNKT) cells recognize abnormal cells, but their T cell receptor is not variable and kill cancerous or infected target cells without MHC I restriction. Here, the authors show that in a clinical trial, donor-unrestricted allogeneic iNKT cells could be safely administered...
医学专题NKT细胞淋巴瘤周剑峰T 和和 NK 细胞肿瘤细胞肿瘤(zhngli)的分类:的分类:WHO 2008WHO 2008: the mature T-cell and NK-cell neoplasmsT-cell prolymphocytic leukemiaT-cell large granular lymphocytic leukemiaChronic lymphoproliferative disorde 2、r of NK-cells*Aggressive NK cell leukemiaSystemic EBV+...
Heczey A, Courtney A, Lui K, et al. Natural killer T cells expressing a GD2-CAR and IL-15 are safe and can induce complete remission in children with relapsed neuroblastoma - a first-in-human, phase 1 trial. Presented at: 2021 American Society of Gene and Cell Therapy Annual Me...
NKT cells are activated in different manners: (1) like T cells, by TCR and recognition of CD1d [24]; (2) like NK cell, by expressing killer cell immunoglobulin-like receptors (KIRs) and natural killer cell receptors (NLRs) [25,26]; and (3) by cytokines like IL-12, IL-18, and in...
Clinical relevance of NK, NKT, and dendritic cell dose in patients receiving G-CSF-mobilized peripheral blood allogeneic stem cell transplantation. Ann Hematol. 2006; 85(2):113. [PubMed: 16311734]Clinical relevance of NK, NKT, and dendritic cell dose in patients receiving G-CSF-mobilized ...
1)NKT cell subsetsNKT细胞亚群 1.Study of the NKT cell subsets with superantigen SEB-activated tolerance;超抗原SEB活化耐受性NKT细胞亚群的研究 英文短句/例句 1.Superantigen SEB-activated natural killer T subsets and its tolerance characteristics超抗原SEB活化的NKT细胞亚群及耐受功能的研究 2.Morphology ...
Li et al. (2015) showed that adoptive transfer of liver NKT cells into T- and B-cell deficient apoE-/-Rag2-/- mice and T-, B- and NK cell deficient apoE-/-Rag2-/-γc-/- mice still augmented atherosclerotic lesion development indicating that neither T and B cells nor NK cells ...
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