The function of NK cells is regulated by a fine balance of inhibitory and activating signals, which are mediated by a diverse array of cell-surface receptors. Natural killer (NK) and natural killer T (NKT) cells represent unique lymphoid subsets of the innate immune system that are both ...
2020年2月 - 4月患者接受NK细胞疗法联合化疗治疗，经过前四个疗程的联合治疗，两肺下叶的线性高密度影...
NK细胞比例下降可能是慢性乙肝致肝组织损伤并能抑制肝炎病。动物实验显示NKT细胞可致肝组织损伤并能抑制肝炎病毒的复制,因此通过调节NK细胞和NKT细胞的功能治疗病毒性肝炎将有可能成为一种新的策略。 NK细胞与肿瘤和癌 NK细胞可以自己寻找畸变的肿瘤细胞和癌细胞等...
Natural killer (NK) and natural killer T (NKT) cells are two important cell subsets of the innate immune system. NK and NKT cells share many phenotypes and functions for anti-tumor immunity; however, the dynamic changes in phenotypes and functional inter
01起效更快 与T细胞相比，NK细胞不需要抗原呈递，起效更快速。02广谱抗癌NK细胞具有更广谱的抗肿瘤作用。
cells. Both NK and NKT cell cytotoxicity and IFN-γ production increase in very old age with respect to normal aging, especially by NKT cells bearing TCRγδ. The role played by zinc and metallothioneins (MT) is crucial because this affects NK and NKT cell development, maturation, and ...
NK, γδ T and NKT cells bridge innate and adaptive responses because although they are of the T cell lineage, they recognize antigens less specifically than αβ T cells, have rapid effects on pathogens, and secrete cytokines influencing B cells and αβ T cells. NK cell activation is con...
1 NK1.1 Vs DX5 expression on NK cells. Splenocytes and hepatic mononuclear cells were isolated from C57BL/6 mice and stained with mAbs specific for CD3, NK1.1, and CD49b b (DX5). Lymphocytes were gated on CD3(−) events to exclude NKT cells. The majority of NK cells coexpress ...
We are dedicated to realizing the potential of natural killer (NK) cells for the treatment of cancer. Our proprietary technology is designed to harness the power of these important pathogen-fighting immune cells and is uniquely capable of enhancing their ability to search and destroy tumor cells....
EBV相关的T和NK细胞LPD(EBV-NKT-LPD)从惰性反应性病变到恶性疾病,显示出广泛的疾病谱。恶性疾病包括系统性侵袭性NK细胞白血病(ANKL,aggressive NK-cell leukemia),结外NK/T细胞淋巴瘤,鼻型(ENKTL,extranodal NK/T-cell lymphoma nasal type)...