在本研究中,对阿替利珠单抗达到完全缓解(CR)和部分反应(PR)的患者被定义为应答者,而病情稳定和进展性疾病(PD)的患者被定义为无应答者。IMvigor210试验的所有数据通过 http://research-pub.gene.com/IMvigor210CoreBiologies/ 下载的IMvigor210CoreBiologies R软件包访问。 TCGA队列中患者的临床病理学特征和基因组数据...
[5] Faustman D, Davis M. TNF receptor 2 pathway: drug target forautoimmune diseases. Nat Rev Drug Discov 2010, 9(6): 482-493. [6] Yokoyama WM, Plougastel BF (2003), Immune functions encoded by the natural killer gene complex. Nat Rev Immunol. 3(4):304-16 [7] Lanier LL (2005)...
Andre´ et al., Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells, Cell, 2018, 175, 1731–1743 Karan Kohli et al,Key chemokines direct migration of immune cells in solid tumors,Canc...
It does not stain the activator form of CD94 which corresponds to the association of CD94 with other products of the NKG2a gene family. The antibody restores the ability of CD94bright NK clones to lyse HLA class I targets. Beckman CD159a (NKG2a)-PC7检测试剂B10246,CD159a-PC7, Z199,...
Results In AML patients receiving immunotherapy, the NKG2A gene variant, rs1983526, was associated with superior leukemia-free survival and overall survival. We observed that superior NK degranulation from individuals with the high-cytotoxicity NKG2D variant was explained by presence of a larger, ...
基因别名:CD159a; Klrc2; NKG2A; NKG2B; NKG2C; Nkg2e Entrez Gene ID:(Mouse) 16641,(Mouse) 16642,(Mouse) 58179 功能 MHC class I protein complex binding
基因别名:CD159a; Klrc2; NKG2A; NKG2B; NKG2C; Nkg2e Entrez Gene ID:(Mouse) 16641,(Mouse) 16642,(Mouse) 58179 功能 MHC class I protein complex binding
查看相关系列 点击查看靶蛋白信息: KLRC1 Accession#: Q9WVJ8 (1) CD159 (3) CD159a (7) Gene ID: 16641 (7) KLRC1 (3) NKG2A (7) 所有研究领域 Skip to the end of the images gallery Skip to the beginning of the images gallery 基本信息 产品名称 NKG2A/CD159a Mouse mAb 别名 杀伤...
NKG2A and NKG2B appear to be splice variants of the same gene and have been given the designation CD159a in the nomenclature of CD antigens. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. 参考文献 Angelini ...
0.5 mg/mL 应用: Flow Cytometry 功能和特点 宿主种属:大鼠(Rat) 种属反应性:小鼠(Mouse) 亚型:Rat IgG2a 克隆号:20D5 偶联:APC 货号(SKU)包装规格是否现货价格数量 Ab191690-10μg(试用装) 申请此免费试用装(?) 10μg现货 原价:¥799.90 +- ...