A large body of evidence that has been generated from animal experiments indicates that treatment with a selective NK1 receptor antagonist might be effective in the treatment of certain forms of anxiety and depressive disorders. Accordingly, numerous NK1 receptor antagonists have either been synthesised...
中文名:NK1 receptor antagonist,英文名:NK1 receptor antagonist,CAS:225655-10-7,化学式:C24H29F3N2O2,分子量:434.49,MSDS.
ReviewofAraipitan-theFirstNK-1ReceptorAntagonist YUKe-fu,HUOJI-ping,ZHUBin,TIANYue,ZHAOZhi-gang * PharmacyDepartment,BeijingTianTanHospital,CapitalMedicalUniversity,Beijing100050,China [Abstract]Chemotherapyisoneofthemostappliedmethodsinthetreatmentoftumor.Nauseaandvomitingwasthecommonphenomenonwhich ...
中文名称: 化合物 NK1 receptor antagonist 2 英文名称: NK1 receptor antagonist 2 CAS号: 579475-17-5 品牌: TargetMol 产地: 美国 保存条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. 产品类别: 抑制剂 货号: T72224 ...
化学名称 NK1 receptor antagonist CAS No.225655-10-7 分子式C24H29F3N2O2 分子量434.503 PubChemID11327981 别名(2S,3S)-N-[[(1R)-6-methoxy-1-methyl-1-(trifluoromethyl)-3,4-dihydroisochromen-7-yl]methyl]-2-phenylpiperidin-3-amine; NK1 receptor antagonist; 查看所有 225655...
Post-injury administration of a substance P, NK1 receptor antagonist attenuated the injury-induced phosphorylation of tau by modulating the activity of several key kinases including Akt, ERK1/2 and JNK, and was associated with improvement in neurological outcome. We also demonstrate that inhibition ...
Prabhakar NR,Snider RM,Lowe JA,et al.Selective blockade of sensory response of the carotidbody to hypoxia by NK, receptor antagonist CP96345.Regulatory Peptides. 1993Prabhakar NR,Snider RM,Lowe JA,et al.Selective blockade of sensory response of the carotidbody to hypoxia by NK, receptor ...
KeywordsNK-1receptorantagonist;Cancerchemotherapy;Antiemetic 作者单位:①大连医科大学(辽宁省大连市116044);②大连市儿童医院 通信作者:**红zhenyhwaner@yahoo 恶心和呕吐至今仍是肿瘤患者接受化学治疗为 不良反应之一。化疗引起的恶心呕吐(CINV)按其发 生时间通常分为急性、迟发性、预期性三种类型。未 予控制的呕吐...
(NK1) receptor antagonist,FK 888, was found to inhibit the electrically-evoked, tachykinin-mediated contractile responses of the rabbit iris sphincter in a concentration-dependent manner; the pIC50 value was 6.6 +/- 0.08. 2. Contractions induced by a selective NK1 receptor agonist, [Sar9,Met...
Description:[D-Arg1,D-Trp7,9,Leu11]-Substance P是一种选择性NK1受体拮抗剂多肽,序列中含有11个氨基酸,包含三个D型氨基酸。 [D-Arg1, D-Trp7,9, Leu11] - Substance P is a selective NK1 receptor antagonist peptide with a sequence of 11 amino acids and three D-type amino acids. ...