一项基于DNA-based NGS panel的大样本回顾性研究分析显示,基于DNA-based NGS检测NTRK融合具有81.1%的总体敏感性和99.9%的特异性,证明了DNA-based NGS对NTRK融合进行检测是可行的。相比于RNA-based NGS,DNA-based NGS检测基因融合受捕获探针覆盖度及DNA层面...
Noninvasive prenatal testing (NIPT) analyzes cell-free DNA from a maternal blood sample to screen for common chromosomal conditions as early as the first trimester.
NGS-based virus testing, a preferred approach to mitigating the virus contamination risk While advanced therapy medicinal products (ATMPs) represent a promising new generation of treatments, they are more vulnerable to viral contaminations that could go undetected by standard methods compared to well...
虽然常规实施NGS分析前,福尔马林固定石蜡包埋(Formalin-Fixed Paraffin-Embedded,FFPE)的组织样本不需要额外的细胞学制备过程,如使用直接涂片法及液基细胞学(Liquid-Based Cytology,LBC)涂片法,然而,美国病理学家学会(College of American Pathologists,CAP)/...
1.Clinical laboratories offering NGS-based testing should perform their own validation of the bioinformatics pipeline 【提供NGS测序的临床实验室都应该执行他们自己校验的生物信息分析流程】 大部分临床实验室应当建立自己的生物信息分析流程。分析流程使用的分析算法和软件工具既有科研用的也有商业化的。而且建立流程中...
The current MSI tests are based on various methodologies, including immunohistochemistry, polymerase chain reactions, or next-generation sequencing (NGS). Each testing methodology has its own technical advantages, but they either fail at liquid biopsy specimen or implement complicated and expensive ...
[9] Nesline M K, Subbiah V, Previs R A, et al. The Impact of Prior Single-Gene Testing on Comprehensive Genomic Profiling Results for Patients with Non-Small Cell Lung Cancer[J]. Oncology and Therapy, 2024, 12(2): 329-343.
【佳学基因】二代测序(NGS)技术应用于临床肿瘤正确医学诊断的共识是中国肿瘤靶向药物基因检测的国家标准。肿瘤基因检测导读:佳学基因是一个充分挖掘基因信息在各个领域的价值的专业
PathoQuest provides biosafety assays based on next-generation sequencing (NGS) for biologics quality testing. GMP biotesting for biopharmaceuticals. Learn more.
The requirements for laboratory space and environmental conditions to support optimal NGS testing The importance of creating a physically separate space for pre- and post-amplification processes in the lab to prevent contamination, as well as...