参考文献1. Shih VF, et al. A single NFκB system for both canonical and non-canonical signaling. Cell Res. 2011;21(1):86-102.2. Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell. 2008;132(3):344-362.3. Christian F, Carmody RJ, et al. The Regulation of NF-κ...
Down-regulated cylindromatosis enhances NF-κB activation and aggravates inflammation in HBV-ACLF patients. Emerg Microbes Infect. 2022;11(1):1586-1601. doi:10.1080/22221751.2022.2077128 Role and mechanisms of the NF-ĸB signaling pathway in various developmental processes Biomed Pharmacother(IF:...
(Chen Y, Wang D, Peng H, et al. Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression.Mol Cance...
High-fat diets induce inflammatory IMD/NFkB signaling via gut microbiota remodeling in Drosophiladoi:10.3389/fcimb.2024.1347716HIGH-fat dietGUT microbiomePERIPHERAL nervous systemDROSOPHILAPATHOLOGYFATHigh-fat diets (HFDs), a prevailing daily dietary style worldwide, induce chro...
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NF-kB Signaling Pathway Nuclear factor kB (NF-kB) is a nuclear transcription factor that regulates expression of a large number of genes that are critical for the regulation of apoptosis, viral replication, tumorigenesis, inflammation, and various autoimmune diseases. The activation of NF-kB is ...
The IKK/NF-kB signaling pathway is key to the linking of metabolism, inflammation, and insulin action. Most of the metabolic stress signals resulting in insulin resistance or pancreatic β cell dysfunction, whether induced by intracellular or extracellular cues, converge on the NF-kB-activating kina...
NF-κB, the ubiquitous nuclear transcription factor, plays a pivotal role in cellular responses to various stimuli across all animal cells. It is involved in inflammation, immune response, cell survival, synaptic plasticity, and memory formation. Notably, its dysregulation is implicated in...
The NF-κB signaling pathway is a crucial regulatory mechanism in cellular responses to various stimuli, including inflammation, immune response, and cell survival. At the core of this pathway lies the transcription factor NF-κB, which plays a pivotal role in gene expression modulation. NF-κB ...
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