蛋白别名:DNA repair protein; I-kappa-B-related protein; ikappaBR; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; tonsoku-like; Tonsoku-like protein ...
Noorolyai S, Shajari N, Baghbani E, Sadreddini S, Baradaran B (2019) The relation between PI3K/AKT signalling pathway and cancer. Gene 698:120–128. https://doi.org/10.1016/j.gene.2019.02.076 Article CAS PubMed Google Scholar Padumadasa C, Dharmadana D, Abeysekera A, Thammitiyago...
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ASSESSMENT OF NFKB CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSIONA bioinformatics process which provides an improved means to detect NFkB cellular signaling pathway in a subject, such as a human, based on the expression levels of at least six unique target...
A third translocation that alters genes involved in the NFKB pathway in human B-lineage tumors is the t(1;14)(p22;q32), which is an uncommon but recurrent event in low-grade MALT B-cell lymphomas. This rearrangement results in the aberrant expression of the BCL10 gene due to its transl...
Thus the nuclear levels of p65 may correlate positively with the activation of NF-kB pathway. Long Name v-rel Reticuloendotheliosis Viral Oncogene Homolog A Alternate Names NFkB p65, NFKB3, p65RelA, nf kb elisa kit, nfkb elisa kit, p65 elisa kit Gene Symbol RELA Additional ...
炎症通路文献 The two NF-kB activation pathways.pdf,Review TRENDS in Immunology Vol.25 No.6 June 2004 The two NF-kB activation pathways and their role in innate and adaptive immunity Giuseppina Bonizzi and Michael Karin Laboratory of Gene Regulation and S
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sequence gene [23], we showed that over-expression of miR-377 decreases the reporter luciferase activity by about 50% (Figure 8A), indicating that miR-377 de- creases the activity along the NF-κB pathway as well. Furthermore, functional analysis of the mRNA expres...
Such responses are mediated to a large degree through changes in gene expression. One transcription factor that serves as a key responder to changes in the environment is NF- B, an evolutionarily conserved signaling module that plays a critical role in many biological processes. Understanding how ...