Official Full Name nuclear factor kappa B subunit 2 Synonyms LYT-10; p52; p105; NF-kB2; p49/p100 Location 10q24.32 Gene Type protein_coding Uniprot ID Q00653.4 Pathway/Library others Gene Summary This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB)....
B Pathway When a person is exposed to a stressful event, their sympathetic nervous system (SNS) -- the system responsible for the 'fight-or-flight' response -- is triggered, in turn increasing production of a molecule called nuclear factor kappa B (NF-kB) which regulates how our genes ...
It is the full-length form of RAGE the one constituting the cellular receptor which is able to activate intracellular signals. After the binding of ligands to RAGE, oxidative stress is increased; then, over-expression of RAGE produces vicious cycles that perpetuate oxidative stress and contribute ...
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corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, ...
Cited in 181 publications. NFKB1,p105,p50 antibody for WB, IF/ICC, FC (Intra), IP, ELISA and reacts with human, rat.
The canonical NF-κB pathway has a prominent role in maintaining the integrity of Treg cell identity, in particular the subset of activated/effector cells. In the periphery, Treg cells can be found in two states: resting Treg (rTreg) are “naïve” cells, the identity of which is controll...
NFkB pathway Cancer Signal transduction Nuclear signaling NFkB pathway Cardiovascular Atherosclerosis Vascular Inflammation Inflammatory mediators Microbiology Interspecies Interaction Host Immune Response Metabolism Types of disease Obesity Applications OurAbpromise guaranteecovers the use ofab16502in the following ...
NF-kB Signaling Pathways 1286 Cell 127, December 15, 2006 ©2006 Elsevier Inc. DOI 10.1016/j.cell.2006.12.005 See online version for legend and references.S n a p S h o t : N F k B S i g n a l i n g P a t h w a y s M ...
Full Name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Synonyms NFKB1, NF kappa B, KBF1, EBP-1, EBP 1 Calculated Molecular Weight 105 kDa Observed Molecular Weight 105 kDa GenBank Accession Number BC051765 Gene Symbol NFKB1 Gene ID (NCBI) 4790 RRID AB_2879299...