JunB的沉默诱导NF-kB激活,由IkBα突变引起的NF-kB沉默阻断了SQSTM1对CXCL10的诱导作用,为了进一步检测NF-kB对细胞因子的表达是否是必需,作者用NF-kB抑制剂PDTC处理细胞,条件培养基被收集并用于分析细胞因子,发现PDTC处理会显著降低促炎症细胞因...
S-294. THE INVOLVEMENT OF ACTIVATED NF-kB AND CCL2 IN THE DEVELOPMENT OF DIABETIC NEUROPATHIC PAINY ZhangY RodriguezM C GitlinK Candiotti
(MCP-1), CCL5 (RANTES), CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF),ICAM1, IFNA1, IFNG, IL8, LTA (TNFB), TNF. Apoptosis: AGT, BCL2A1 (BCL-X), BCL2L1, BIRC3 (c-IAP1). Other Factors Involved in NFκB Pathway: Kinases: AKT1, MAP3K1, RAF1. Transcription Factors: ATF1,...
图3 HBV-ACLF患者与CHB及正常对照肝组织中CXCL5、CXCL6、CXCL8、CCL2、CCL5和CCL20的表达水平 这6个趋化因子对应的靶细胞T细胞,巨噬细胞,中性粒细胞和NK细胞在HBV-ACLF患者肝脏浸润的数量也显著增高。HBV-ACLF患者肝脏HE染色显示显著的...
Extracellular and Adhesion Molecules: AGT, CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF), ICAM1, IFNA1, IFNG. Cytokines: CCL2 (MCP-1), CCL5 (RANTES), CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF), IFNA1, IFNG, IL8, IRF1, LTA (TNFB), TNF. ...
Pathway Activity Signature Genes: BIRC3, CCL20, CD83, CXCL2, CXCL3, ICAM1, IL8, IRF1, NFKB1, NFKBIA, NFKBIE, STX11, TIFA, TNF, TNFAIP2, TNFAIP3. NFkB 信号通路PCR芯片NFkB Signaling Pathway PCR Array由上海英拜生物科技有限公司 为您提供,如您想了解更多关于NFkB 信号通路PCR芯片NFkB ...
Apoptosis: BCL2A1 (Bfl-1/A1), BCL2L1 (BCL-X), BIRC3 (c-IAP1).Other Factors Involved in the NFκB Pathway: Ligands and Receptors: IL1R1, RAF1, TLR7, TLR9.Kinases: AKT1, RAF1.Transcription Factors: ATF1, EGR1, ELK1, FOS, JUN, TNFAIP3.Inflammatory Response: CCL2 (MCP-1), ...
CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-kappaB signaling pathway. Biochemical pharmacology. 83:335-344. :Tang CH; Tsai CC.CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ ...
NF-κB是对有害细胞刺激的第一反应者。已知的NF-κB通路激活的炎症与免疫相关的因子有很多，包括促炎细胞因子（TNF-α、IL-1β、IL-6、IL-12、趋化因子(CXCL8（IL-8）、CCL2（MCP-1）、CCL5（RANTES）)、免疫受体（CD80/CD86）、抗原提呈分子（MHC I/II类分子）等。细胞存活与凋亡调控基因如：抗凋亡蛋白...