Presents a study which investigated the influence of hyperoxia on the nitric oxide pathway in rat alveolar macrophages in vitro, its regulation by the transcription factors nuclear factor and activator protein.
Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell- free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation. J Biol Chem 1995;270:21707-14.Orian A,Gonen H,...
Moreover, a NF-kB inhibitor (PDTC) and an activator (TNF) were used before mechanical stretch. Realtime PCR and ELISA were performed to detect the mRNA and protein of IL-8, respectively. The results showed that the mechanical cyclic stretch led to increased Cyr61 expression at mRNA and ...
In this study, HepG2 cells were used to investigate the role of HSD17B4 in the proliferation of liver cancer cells treated with the NE-kappa B activator, tumor necrosis factor-alpha (TNE-alpha), with the inhibitor of NE-kappa B activation, pyrrolidinedithiocarbamate (PDTC), or with a ...
SIRT1 activator (resveratrol) and inhibitor (EX527) were administered intraperitoneally 1 h after SAH induction. Twenty-four hours after SAH, the VSMC contractile phenotype marker alpha-smooth muscle actin (alpha-SMA) decreased, whereas the VSMC synthetic phenotype marker embryonic smooth muscle ...