Neutrophil depletion with Gr-1 mAb elicits emergency granulopoiesis with minimal inflammation.Derek W. CainPilar B. SnowdenGregory D. SempowskiGarnett Kelsoe
Depletion of GR-1-Positive Cells Is Associated with Reduced Neutrophil Inflammation and Astrocyte Reactivity after Experimental Intracerebral Hemorrhage[J] . Matthew Loftspring,Holly Johnson,Aaron Johnson,Joseph Clark.Translational Stroke Research . 2012 (1)...
Thus, ZBP1-mediated IL-1α production is the key initial step of IAV-infected NETs, regulating the duality of the consequent lung inflammation. 展开 关键词: IL-1 ZBP1 influenza virus innate immunity neutrophil DOI: 10.1093/intimm/dxz070 年份: 2020 ...
Marion Gr?gerTetsuri MatsumuraNorbert KohrgruberDieter MaurerKlaus WolffPeter PetzelbauerJournal of Immunological MethodsGroger, M.; Matsumura, T.; Kohrgruber, N.; Maurer, D.; Wolff,K.; Petzelbaue~, P. A standardized, computer-assisted in vitro assay for the assessment of neutrophil ...
Grigoryants V, Hannawa KK, Pearce CG, Sinha I, Roelofs KJ, Ailawadi G, Deatrick KB, Woodrum DT, Cho BS, Henke PK, Stanley JC, Eagleton MJ, Upchurch GR. Tamoxifen up-regulates catalase production, inhibits vessel wall neutrophil infiltration, and attenuates development of experimental ...
Indonesia is significantly affected by the emergence of the Omicron variant during the coronavirus disease 2019 COVID-19 pandemic, with one of the most prominent case increases on February 2022 (third wave of the pandemic). Several factors, ranging from demographics to laboratory tests, have been ...
Lawton JW, Costello C, Barclay GR, Urbaniak SJ, Darg C, Raeburn JA, Uttley WS, Kay AB. The effect of transfer factor on neutrophil function in chronic mucocutaneous candidiasis. Br J Haematol. 1976 May; 33 (1):137–142.Lawton, J. W. M., Costello, C., Barclay, G. R., Urbani...
To study the function of neutrophils in vivo, these cells are often depleted using Ly-6G or Gr-1 depleting antibodies or genetic "knockout" models. However, these methods have several limitations, being only partially effective, effective for a short term, and lacking specificity or the ability...
PMN were depleted by intraperitoneal Gr-1 antibody injection. Pharmacological HIF stabilization was achieved via daily subcutaneous injection of AKB-4924. Disease progression was monitored via weight loss. RESULTS. Microarray profiling of transcriptional changes induced in epithelia following exposure to ...
Riepl Birgit,Gr?ssel Susanne,Wiest Reiner,Fleck Martin,Straub Rainer H.Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis. Arthritis research & therapy . 2010...