2.3.3.3 Mast cells/eosinophilic granule cells Cells with structural and functional properties resembling those of mammalian mast cells (MCs) have been described in the digestive tract, gills, and other tissues of most teleosts. These cells present a characteristic basic staining of the cytoplasmic gr...
granule- a tiny grain microsome- a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA chondrule- small granule (of e.g. chrysolite) found in some meteoric rocks grain- a relatively small granular particle of a substance; "a grain of sand...
, hCAP-18 (human cationic antimicrobial protein) andNGAL(a matrix protein). A third type of granule contains gelatinase but little or no lactoferrin (gelatinase granules) and neutrophils also containsecretory vesicleswith molecules such as β2-integrins, formylpeptide receptors andCD14. The secretory...
Neutrophils are granule-containing, polymorphonuclear leukocytes that develop in the bone marrow from myeloid precursors. ... In addition,CD66b/CEACAM-8, CD11b/Integrin alpha M, CD33, and the cytoplasmic marker, myeloperoxidase, are other common markers that are used to identify human neutrophils. ...
Christoph Klein and colleagues identify loss-of-function mutations in SMARCD2 (BAF60b) that lead to neutropenia, specific granule deficiency and myelodysplasia. They show that SMARCD2 controls differentiation of myeloid–erythroid progenitor cells throug
Technological advances have greatly improved our knowledge of myelopoiesis, for example, with the discovery of granulocyte‒monocyte‒dendritic cell (DC) progenitors (GMDPs), monocyte‒DC progenitors (MDPs), common DC progenitors (CDPs) and common
fluorescence (Zeiss Ax10) microscopes, and LasX and AxioVision softwares, respectively. Brightness, contrast and color of digital images were adjusted with Adobe Photoshop CS5 v12.0 program (Adobe Systems Inc.). HIV-1 infection and effects of NETs on HIV-1 replication...
In the CC enrichment analysis, secretory granule membranes and intracellular vesicles were the most enriched CCs. The most enriched MF terms were anticipatory activity and phospholipid binding. In addition, we performed the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis to identify DEG-...
Rac2 is critical for neutrophil primary granule exocytosis Blood, 104 (2004), pp. 832-839 View PDFView articleView in ScopusGoogle Scholar 58 R.H. Ingraham, R.D. Gless, H.Y. Lo Soluble epoxide hydrolase inhibitors and their potential for treatment of multiple pathologic conditions Curr Med ...
RNA sequencing of LDGs compared with NDGs reveals upregulation of granule proteins and adhesion molecules To understand the relationship between psoriasis LDGs and NCB, which is a relationship not observed with psoriasis NDGs, we studied RNA expression between these neutrophil subsets derived from 7 ...