Azurophil granules are discharged only when neutrophils interact with phagocytizable particles, whereas specific granules are discharged on interaction of the cells with both particulate and soluble stimuli. In the latter case, specific granule constituents are released directly into the extracellular ...
(NE). A serine protease stored in the neutrophil intracellular granules. Circulating tumour cells (CTCs). Cancer cells that have detached from a primary tumour and are found in the bloodstream. Pre-metastatic niche An environment in a secondary organ that provides favourable conditions for the seed...
These findings suggest that even though DMSO-differentiated PLB-985 cells did not possess the same granules as human neutrophils, the “NETosis” capabilities of these differentiated cells are similar to that of human neutrophils. Our data altogether show that PLB-985 cells are different from ...
Neutrophil:A type of white blood cell, a granulocyte that is filled with microscopic granules, little sacs containing enzymes that digest microorganisms. Also known aspolymorphonuclear leukocyteor poly.
Neutrophil granules and secretory vesicles in inflammation The neutrophil is a major effector cell of innate immunity. Exocytosis of granules and secretory vesicles plays a pivotal role in most neutrophil functions... M Faurschou,N Borregaard - 《Microbes & Infection》...
Vascular injury triggers endothelial exocytosis of granules, releasing pro-inflammatory and pro-thrombotic mediators into the blood. Nitric oxide (NO) and ... CJ Lowenstein,H Tsuda - 《Biological Chemistry》 被引量: 172发表: 2006年 Peroxynitrite and nitric oxide donors induce neuronal apoptosis by...
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Noun1.granulocyte- a leukocyte that has granules in its cytoplasm leucocyte,leukocyte,WBC,white blood cell,white blood corpuscle,white cell,white corpuscle- blood cells that engulf and digest bacteria and fungi; an important part of the body's defense system ...
lipocalin. Examples areretinol binding protein, which transportsvitamin A, or lipocalin α 1-microglobulin, which metabolizes the heme group.NGALwas initially identified as a protein bound togelatinaseinneutrophils, where it constitutes one of the proteins of the secondary granules (see Haase et al....
Lipocalin 2 (Lcn2) is a 25-kDa glycoprotein that has initially been extracted from neutrophil granules. Expression of Lcn2 is induced under various pathophysiological conditions. It is also known as an early marker of kidney and heart injury. High-level expression of recombinant Lcn2 neutrophil ...