2005. Proteomic analysis of human neutrophil granules . Mol. Cell. Proteomics. 4 :1503–1521 10.1074/mcp.M500143-MCP200 [ Cross Ref ]Lominadze G., Powell D. W., Luerman G. C., Link A. J., Ward R. A., McLeish K. R. (2005) Proteomic analysis of human neutrophil granules . ...
(NE). A serine protease stored in the neutrophil intracellular granules. Circulating tumour cells (CTCs). Cancer cells that have detached from a primary tumour and are found in the bloodstream. Pre-metastatic niche An environment in a secondary organ that provides favourable conditions for the seed...
Neutrophil:A type of white blood cell, a granulocyte that is filled with microscopic granules, little sacs containing enzymes that digest microorganisms. Also known aspolymorphonuclear leukocyteor poly.
(2018). Armed for destruction: formation, function and trafficking of neutrophil granules. Cell Tissue Res. 371, 455-471. doi: 10.1007/ s00441-017-2731-8Yin C, Heit B (2018) Armed for destruction: formation, function and trafficking of neutrophil granules. Cell Tissue Res. https://doi....
Neutrophil granules and secretory vesicles in inflammation The neutrophil is a major effector cell of innate immunity. Exocytosis of granules and secretory vesicles plays a pivotal role in most neutrophil functions... M Faurschou,N Borregaard - 《Microbes & Infection》...
Vascular injury triggers endothelial exocytosis of granules, releasing pro-inflammatory and pro-thrombotic mediators into the blood. Nitric oxide (NO) and ... CJ Lowenstein,H Tsuda - 《Biological Chemistry》 被引量: 172发表: 2006年 Peroxynitrite and nitric oxide donors induce neuronal apoptosis by...
Human granulocytes are classically characterized by their capacity to act as phagocytes, degranulators secreting preformed lytic enzymes from their granules, and produce reactive oxygen species (ROS) to destroy bacteria, parasites, and fungi. Basophils and eosinophils are mainly involved in the defense...
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lipocalin. Examples areretinol binding protein, which transportsvitamin A, or lipocalin α 1-microglobulin, which metabolizes the heme group.NGALwas initially identified as a protein bound togelatinaseinneutrophils, where it constitutes one of the proteins of the secondary granules (see Haase et al....
As professional phagocytes, they engulf bacteria and kill them intracellularly when their antimicrobial granules fuse with the phagosome. We found that neutrophils have an additional way of killing microorganisms: upon activation, they release granule proteins and chromatin that together form extracellular ...