根岸偶联反应(Negishi coupling)是一个有机反应。反应中,有机锌试剂(英语:organozinc compound)与卤代烃在镍或钯的配合物的催化下发生偶联,生成一根新的碳-碳键[1][2]: 其中, 卤素X可以是氯、溴或碘,也可以是其它的基团,如三氟甲磺酰基(英语:triflate)或乙酰氧基,而基团R则可以是烯基、芳基、烯丙基、炔...
根岸偶联反应(Negishi coupling)是一个有机反应。反应中,有机锌试剂(英语:organozinc compound)与卤代烃在镍或钯的配合物的催化下发生偶联,生成一根新的碳-碳键[1][2]: 其中, 卤素X可以是氯、溴或碘,也可以是其它的基团,如三氟甲磺酰基(英语:triflate)或乙酰氧基,而基团R则可以是烯基、芳基、烯丙基、炔...
论文信息: Enantioselective Construction of C-SCF3 Stereocenters via Nickel Catalyzed Asymmetric Negishi Coupling Reaction Duo-Duo Hu, Tian-Mei Nie, Xi Xiao, Kuiliang Li, Yuan-Bo Li, Qian Gao, Yu-Xiang Bi, Xi-Sheng Wang Angewandte Chemie International Edition DOI: 10.1002/anie.202400308 来源:W...
The first experimental observations on the transmetalation step in the Negishi coupling were recently reported by Espinet et al. for the transmetalation reaction between trans-[Pd(Rf)(Cl)(PPh\\(_3\\))\\(_2\\)] (Rf = 3,5-dichloro-2,4,6-trifluorophenyl) and the organozinc reagents ...
coupling reactions, especially with Pd, Ni and new type Fe, Co as catalysts wasreviewed. The prospect of the new catalysts was presented.KeywordsOrganozinc, Negishi cross-coupling reaction, Transition metal catalyst systemNegishi 偶联反应是有机锌试剂与卤代烃在过渡金属或过渡金属配合物催化下偶联生成新...
negishi根岸偶联反应coupling苯基催化剂 根岸偶联反应(Negishicoupling)是一个有机反应。反应中,有机锌试剂与卤代烃在 镍或钯的配合物的催化下发生偶联,生成一根新的碳-碳键 [1] [2] : 其中, 卤素X可以是氯、溴或碘,也可以是其它的基团,如三氟甲磺酰基或乙酰氧基, 而基团R则可以是烯基、芳基、烯丙基、炔...
图式 1 Negishi 偶联反应机理示意图Scheme 1 Schematic diagram of Negishi coupling reaction mechanism2发展概况自从发现 Negishi 偶联反应以来,钯和钯的络合物作为催化剂催化 Negishi 偶联反应是应用最多的,人们最近还实现了各种配体参与的钯催化剂催化的 Negishi偶联反应; 此外,已经报道的能够催化 Negishi 偶联的金属...
关键词有机锌Negishi反应过渡金属催化剂体系 ProgressinNegishiCross-couplingReactions ShaoZhongqi,LiXing,ChangHonghong,WeiWenlong * (CollegeofChemistryandChemicalEngineering,TaiyuanUniversityofTechnology,Taiyuan030024) AbstractThemechanismofNegishicross-couplingreactionsinpresenceoforganozincreagentsisdescribedin brief.The...
The Negishi coupling is the nickel- or palladium-catalyzed reaction between aryl or vinyl halides (or triflates) with organozinc halides. The reaction was first reported by Ei-ichi Negishi in 1977. Several reviews have been published. Mechanism of the Negishi Coupling ...
Negishi Cross-Coupling Reactions Catalyzed by an Aminophosphine-Based Nickel System: A Reliable and General Applicable Reaction Protocol for the High-Yielding Synthesis of Biaryls 作者:Gerber Roman; Frech Christian M* 来源:Chemistry - A European Journal, 2011, 17(42): 11893-11904. DOI:10.1002/...