论文信息: Enantioselective Construction of C-SCF3 Stereocenters via Nickel Catalyzed Asymmetric Negishi Coupling Reaction Duo-Duo Hu, Tian-Mei Nie, Xi Xiao, Kuiliang Li, Yuan-Bo Li, Qian Gao, Yu-Xiang Bi, Xi-Sheng Wang Angewandte Chemie International Edition DOI: 10.1002/anie.202400308 来源:W...
商业转载请联系作者获得授权,非商业转载请注明出处。 粗略说说,如果只是讨论偶联反应(cross coupling reaction)的话,考虑偶联反应的基本步骤就好了。 一般偶联反应都从零价Pd启动,经历氧化加成(oxidative addition),转金属化(transmetallation),还原消除(reductive elimination)。那么对于各个步骤,不同的配体有不同的表现,...
A series of isocombretastatins A has been synthesized by a new method based on the Negishi cross-coupling reaction in 19-84% yields. Five of the synthesized compounds exhibit high cytotoxic activity in nanomolar concentrations (IC_(50) = 1-100 n) towards Jurkat, K562, Colo357, and A549 ...
A series of isocombretastatins A has been synthesized by a new method based on the Negishi cross-coupling reaction in 19–84% yields. Five of the synthesized compounds exhibit high cytotoxic activity in nanomolar concentrations (IC50 = 1–100 nМ) towards Jurkat, K562, Colo357, and A549 cell...
Negishi cross-coupling reactions catalyzed by an aminophosphine-based nickel system: a reliable and general applicable reaction protocol for the high-yielding synthesis of biaryls Chemistry (Weinheim an der Bergstrasse, Germany)Gerber R, Frech CM (2011) Negishi cross-coupling reactions catalyzed by an...
Negishi Cross-Coupling Reactions Catalyzed by an Aminophosphine-Based Nickel System: A Reliable and General Applicable Reaction Protocol for the High-Yielding Synthesis of Biaryls 作者:Gerber Roman; Frech Christian M* 来源:Chemistry - A European Journal, 2011, 17(42): 11893-11904. DOI:10.1002/...
根岸耦合反应
1. Erratum: Negishi cross-coupling reaction catalyzed by an aliphatic, phosphine based pincer complex of palladium. biaryl formation via cationic pincer-type Pd ~(IV) intermediates (Dalton Transactions (2011) 40 (8996) DOI: 10.1039/C1DT10398A) [J] . Gerber R., Blacque O., Frech C.M. ...
Negishi cross-coupling reaction catalyzed by an aliphatic, phosphine based pincer complex of palladium. biaryl formation via cationic pincer-type Pd-IV intermediates. Roman Gerber,Olivier Blacque,Christian M. Frech. Dalton Transactions . 2011
NegishiCouplingINCLUDEPICTURE"http://anic-chemistry/namedreactions/negish2.gif"\*MERGEFORMATINETTheNegishiCoupling,publishedin1977,wasthe..