Negative feedback loops are well known in physiology. Previous work at UCLA has identified a negative feedback pathway involving Bone Morphogenetic Protein 4 (BMP-4) and an inhibitor of BMP-4 called Matrix Gla Protein (MGP) active in vascular development and pathology. More recently, other ...
Oscillations control many important aspects of cell physiology15, including circadian rhythms16, DNA synthesis, mitosis17,18, and the development of somites in vertebrate embryos19. Homeostasis ensures the stability of essential biological parameters such as body temperature, blood sugar levels, and blood...
Learn the difference between positive and negative feedback. Understand what is positive feedback in biology through the use of some positive...
physiology and pathophysiolgy, little is known about the transcriptional regulation of its main components. Here, we found that ankyrin-G and IKKα/β co-localized in membrane and synaptosomal fractions of mouse cortical extracts and co-immunoprecipitated from cortical lysates, also evidenced in the ...
1.4 Physiology of the Endocannabinoid System 1.4.1 Mechanisms Underlying the Retrograde Control of Synaptic Signaling Endocannabinoids, particularly 2-AG, act as retrograde messengers in the CNS. This negative feedback mechanism is conserved at glutamatergic synapses in the spinal cord, midbrain, striatum...
2013, American Journal of Physiology - Lung Cellular and Molecular Physiology NF-κB-inducing kinase plays an essential T cell-intrinsic role in graft-versus-host disease and lethal autoimmunity in mice 2011, Journal of Clinical Investigation View all citing articles on Scopus Supported by the Nation...
M Nagae,M Nakata,Y Takahashi - 《Plant Physiology》 被引量: 130发表: 2008年 The Iron Control Element, Acting in Positive and Negative Control of Iron-Regulated Bradyrhizobium japonicum Genes, Is a Target for the Irr Protein Bradyrhizobium japonicum, the nitrogen-fixing soybean symbiont, possesses...
6.PhysiologyA turning of both eyes outward from a common point or of one eye when the other is fixed. 7.MeteorologyA condition characterized by the uniform expansion in volume of a mass of air over a region, usually accompanied by fair dry weather. ...
4). This strongly suggested that increasing concentrations of circulating TNFα were perceived by liver cells as increases in pulse duration, also plausible given the dual re-circulation physiology of the liver (hepatic arterial and portal venous) as well as bioavailability and hemodilution effects. ...
Background: Growth factors and their receptor tyrosine kinases play pivotal roles in development, normal physiology, and pathology. Signal transduction is regulated primarily by receptor endocytosis and degradation in lysosomes (“receptor downregulation”). c-Cbl is an adaptor that modulates this process...