摘要: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent of HMG-CoA reductase inhibitors or erythropoietin. The nanoparticles are characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery....
This invention relates to a unique process for the preparation of polymeric nanoparticles with target molecules bonded to the surface of the particles and having sizes of up to 1000nm, preferably Inm to 400nm, more preferably Inm to 200nm, that are dispersed homogeneously in aqueous solution. ...
Nanoparticles Designed for Drug Delivery 优质文献 相似文献 参考文献 引证文献Biodegradable nanoparticles designed for drug delivery: The number of nanoparticles impacts on cytotoxicity Nanostructured drug delivery systems are based on biocompatible and biodegradable components. Composition, size and membrane surfac...
Nanoparticles are undergoing extensive exploration for targeted drug delivery. Currently, nanocarriers often suffer from low efficacy and cause side effects to healthy tissues. The uptake and removal of nanoparticles dictate their internal concentration inside cells and thus the efficacy and toxicity of the...
Nanoparticulate systems made of biopolymers encompass promising properties as carriers and adjuvant for drug delivery. Alginate is one of the most widely investigated biomaterials in the field of nanoparticulate drug delivery due to its ... MS Hasnain,AK Nayak,M Kurakula,... - 《Alginates in Dru...
Objective To review the advances on chitosan nanoparticles for drug delivery.Methods According to recent references,the preparative method,release characteristics,bio-uptake and application of chitosan nanoparticles are summarized.Results Different preparative method can make chitosan nanoparticles with different ...
Multifunctional Drug and Gene Delivery Nanoparticles for Targeted Cancer Therapy. Drug nanocarriers are of great interest for targeted cancer therapy due to their passive (via the enhanced permeability and retention (EPR) effect) and act... G Chen - The University of Wisconsin - Madison. 被引量:...
nanoparticles for oral delivery of peptides and proteins targeting of nanoparticles to epithelial cells in the GI tract using ligands 使用配体将纳米颗粒靶向胃肠道中的上皮细胞 nanoparticle for gene delivery for drug delivery into the brain分享到: 投诉或建议 ...
mesoporoussilicananoparticlesdrugdeliverymsns DOI:10.1002/adfm.200601191MesoporousSilicaNanoparticlesforDrugDeliveryandBiosensingApplications**ByIgorI.Slowing,BrianG.Trewyn,SupratimGiri,andVictorS.-Y.Lin*1.IntroductionRecentbreakthroughsinthesynthesisofmesoporoussilicamaterialswithcontrolledparticlesize,morphology,andporosi...