为了规范NAFLD的筛查、诊断、治疗、随访,中华医学会肝病学分会在2018年发布了《非酒精性脂肪性肝病防治指南(2018更新版)》,极大推动了NAFLD的规范化诊疗。2020年,国际脂肪肝专家组建议NAFLD更名为MAFLD,同年亚太肝病学会发布MAFLD诊疗指南。然而,2023年以...
为了规范NAFLD的筛查、诊断、治疗、随访,中华医学会肝病学分会在2018年发布了《非酒精性脂肪性肝病防治指南(2018更新版)》,极大推动了NAFLD的规范化诊疗。2020年,国际脂肪肝专家组建议NAFLD更名为MAFLD,同年亚太肝病学会发布MAFLD诊疗指南。然而,2023年以美国肝病学会为首的多学会声明建议将NAFLD更名为MASLD。就此更名问...
MAFLD的定义可能更加复杂,因此在预测全因死亡率和心血管相关死亡率时表现较差。事实上,MAFLD的诊断标准包括心脏代谢特征和非特异性血清学指标,如C反应蛋白和胰岛素抵抗的稳态模型评估(HOMA-IR)。此外,MAFLD的诊断标准未考虑饮酒因素,这进一步增加了死亡风险评估的复杂性。 NAFLD与MASLD的主要区别在于MASLD的诊断标准将其他...
MASLD比MAFLD更加强调代谢性心血管危险因素在NAFLD发病中的作用,对于BMI正常且无糖尿病的脂肪性肝病患者,只要存在1项代谢性心血管危险因素就可诊断MASLD,而MAFLD的诊断则至少需2项代谢性心血管危险因素。MASLD更名过程中认为英文单词"fatty"也有污...
NAFLD was not associated with all‐cause mortality. However, all three terms were associated with an increased risk of all‐cause mortality in individuals with advanced fibrosis (aHR: 1.71–1.81). Subgroup analyses showed that higher risk of all‐cause mortality for both MAFLD and MASLD ...
NAFLD renaming to MAFLD,MASLD:background,similarities,differences,and countermeasures 引用 收藏 分享 摘要 非酒精性脂肪性肝病(NAFLD)是遗传易感个体由于长期营养过剩导致的慢性代谢应激性肝损伤。随着肥胖、糖尿病和代谢综合征的流行,NAFLD已成为全球第一大慢性肝病,而沿用40年的排他性疾病诊断标准和带有污名化问题...
Chapter 27 - Metabolic-Associated Fatty Liver Disease (MAFLD): Nonalcoholic Fatty Liver Disease/Metabolic Dysfunction–Associated Steatotic Liver Disease (NAFLD/MASLD) and Metabolic Dysfunction–Associated Steatohepatitis (MASH) 来自 dx.doi.org 喜欢 0 阅读量: 8 作者:...
Participants were categorized according to NAFLD, MAFLD, MASLD, and sub-classifications of SLD. Results: The prevalence rates of NAFLD, MAFLD, and MASLD were 25.9%, 29.5%, and 25.2%, respectively. 30.5% of the participants was categorized as SLD. The prevalence rates of the SLD sub-...
Comparing similarities and differences between NAFLD, MAFLD, and MASLD in the general U.S. populationdoi:10.3389/fnut.2024.1411802Haoxuan ZouXiaopu MaWen PanYan XieFrontiers in Nutrition
Purpose: International expert panels proposed new nomenclatures, metabolic dysfunction-associated fatty liver disease (MAFLD) in 2020 and metabolic dysfunction-associated steatotic liver disease (MASLD) in 2023, along with revised diagnostic criteria to replace non-alcoholic fatty liver disease (NAFLD). ...