Thomas J. SimpsonDavid I. SmithPaul WattsChristine L. WillisJohn Wiley & Sons, Ltd.ChemInformSann et al., " A General Synthesis of Homochiral beta-Hydroxy N-Acetylcysteamine Thioesters, " Tetrahedron Letters (1999) 40(21):4093-4096.
L. (1995) Synthesis of β-keto and α, β-unsaturated N-acetylcysteamine thioesters. Bioorg. Med. Chem. Lett. 5, 1587-1590Gilbert, I.H., Ginty, M., O'Neill, J.A., Simpson, T.J., Staunton, J. & Willis, C.L. (1995). Synthesis of β-keto and α,β-unsaturated N- acetyl...
[68] Synthesis of thioesters of N-acetylcysteaminedoi:10.1016/S0076-6879(69)14071-9KassLeon R.ELSEVIERMethods in EnzymologyKass, L. R. and Broch, D. J. H., Synthesis of thioesters of N acetylcysteamine. Methods Enzymol., 14, 696-698 (1969)....
Thomas J. SimpsonSch. Chem.David I. SmithSch. Chem.Paul WattsSch. Chem.Christine L. WillisSch. Chem.ChemInformSann et al., " A General Synthesis of Homochiral beta-Hydroxy N-Acetylcysteamine Thioesters, " Tetrahedron Letters (1999) 40(21):4093-4096....
Staunton, and C. L. Willis. 1995. Synthesis of -keto and ␣,-unsaturated N-acetylcysteamine thioesters. Bioorg. Med. Chem. 5:1587-1590.Sann et al., " A General Synthesis of Homochiral β-Hydroxy N-Acetylcysteamine Thioesters, " Tetrahedron Letters (1999) 40(21):4093-4096....
Gilbert, I. H., M. Ginty, J. A. O'Neill, T. A. Simpson, J. Staunton, and C. L. Willis. 1995. Synthesis of -keto and ␣,-unsaturated N-acetylcysteamine thioesters. Bioorg. Med. Chem. 5:1587-1590.Gilbert, I.H., Ginty, M., O'Neill, J.A., Simpson, T.J., ...
Apparent kinetic constants k"c"a"t and K"m were determined for tyrocidine thioesterase (TycC TE) using randomized peptide N-acetylcysteamine thioesters as substrate analogues. The enzyme has been found to be adequately active for the synthesis of positional-scanning libraries for novel antibiotic...
Biomimetic N-acetylcysteamine thioesters are essential for the study of polyketide synthases, non-ribosomal peptide synthetases and fatty acid synthases. The chemistry for their preparation is, however, limited by their specific functionalization and their susceptibility to undesired side reactions. Here ...
Kass L R.The antibacterial activity of 3-decynoyl-n-acetylcysteamine. Inhibition in vivo of beta-hydroxydecanoyl thioester dehydrase.Journal of Biological Chemistry. 1968Kass, L.R. 1968 . The antibacterial activity of 3-decynoyl-N-acetylcysteamine. Inhibition in vivo of β-hydroxydecanoyl ...