For proteins having a Lys or Arg at the N-terminus with a (LFPT) leucine / phenylalanine -tRNA protein transferase enzymes with the ability to add a Leu or Phe in the end, the present invention is modified from a modified phenylalanine by an addition to the N-terminal arginine and ...
N-末端选择性蛋白质修饰 N-Terminus Selective Protein Modification N末端在蛋白质的一条链中只有一处,因此以此为靶点的修饰反应必然的可以实现高位置・化学选择性,并且能够得到均质的修饰体。这样的修饰对高次结构的影响也比较小。另外大概有80%的蛋白质,其N末端都是裸露在蛋白质表面的,因此,该修饰法的活用就显...
Acetylation of protein N-termini underlies several key biological processes. Although NatC acetylates hundreds of different substrates, we know very little about the functional and physiological importance of these acetylation events. While the genes encoding the human NatA and NatB subunits are mostly ...
A growing number of N-terminus-specific enzymatic ligation strategies have provided additional possibilities. This Perspective provides an overview of N-terminal modification techniques and the chemical rationale governing each. Examples of specific N-terminal protein conjugates are provided, along with ...
The protein consists of 462 a.a. with a 23a.a. signal peptide at N-terminus, and is further cleaved into SHH N-Terminus and C-Terminus. SHH has the most critical roles in development, acting as a morphogen involved in patterning many systems, including the limb and midline structures in...
The N-terminus of murine leukaemia virus p12 protein is required for mature core stability. 2014. The N-terminus of murine leukaemia virus p12 protein is required for mature core stability. PLoS Pathog 10: e1004474. https://doi.org/10.1371/... Darren,J,Wight,... - 《Plos Pathogens》 ...
S4B). Based on these findings, we were wondering whether the other polybasic motif, located at the very N terminus, has a similar function in LLPS. N1•PB1>A did also not undergo LLPS and formed assemblies with irregular structures, indicating a gel-like or aggregated state, as judged ...
免疫原 Peptide with sequence EVQLGLGRVYPRPPSC, from the N Terminus of the protein sequence according to NP_000035.2. 特异性 This antibody is expected to recognize isoform 1 (NP_000035.2) only. 交叉反应 小鼠, 大鼠, 犬, 猪, 牛 纯化方法 Purified from goat serum by ammonium sulphate precip...
The N terminus of phosducin is involved in binding of beta gamma subunits of G protein Phosducin is a soluble phosphoprotein found in retinal photoreceptor cells and in the pineal gland. It binds to the βγ subunits of guanine nucleotide-bin... J Xu,D Wu,VZ Slepak,... - 《Proceedings ...
免疫原Peptide with sequence STVHEILCKLSLEGD, from the N Terminus of the protein sequence according to NP_001002858.1, NP_004030.1, NP_001002857.1, NP_001129487.1. 特异性This antibody is expected to recognise both reported isoforms. NP_004030.1, NP_001002857.1and NP_001129487.1 are varients of isofo...