The Ritter reaction has been successfully extended to the direct preparation of N-glycosidic bond-linked nonionic carbohydrate-based surfactants from carbohydrates and nitriles in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) and silver perchlorate (AgClO4) on a high-speed mechanical...
Chemistry: A European journalG. Malik, A. Ferry, X. Guinchard, T. Cresteil, D. Crich, N-O bond as a glycosidic- bond surrogate: synthetic studies toward polyhydroxylated N-alkoxypiper- idines, Chem. Eur. J. 19 (2013) 2168e2179....
was found to carry Man-8 and Man-9 oligomannosides containing 6-O-methyl mannose and substituted by one or two xylose residues (11). In contrast, glycans N-linked to proteins secreted by the diatom P. tricornutum can be processed through a GnT I-dependent pathway into paucimannosidic ...
they are both inverting GTs, i.e. they catalyze the formation of a glycosidic bond with inversion of configuration of the donor anomeric carbon22,23. They also share the Asn0-X+1(X ≠ P)-Ser/Thr+2conserved sequence motif in their protein...
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. Subunit: Belongs to the DNA glycosylase MPG family. Subcellular Location: Nucleus. Similarity: ...
ait hydrolyses the β-(1,4)-glycosidic bond between the alternating N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) in the peptidoglycan 它在peptidoglycan(水解)β- 1,4 - glycosidic债券在 (交替的) N-acetylmuramic酸 (NAM) 和N-acetylglucosamine老马之间 [translate] ...
As the A2660 region has been shown to interact with the elongation factors EF-Tu and EF-G these results indicate that MAP cleaves the N-glycosidic bond at A2660 in E. coli 23 S RNA resulting in the inactivation of the ribosome. 展开 关键词: RIBOSOME RIBOSOMAL-RNA N-GLYCOSIDASE RIBOSOME-...
Kinetic parametrs for enzymatic cleavage of the glycosidic bond (phosphorolysis) of ten N(7)-substituted guanosines were determined, and used to establish a structure-activity relation for the Michaelis constants. Results were compared with those for acid-catalyzed cleavage of the glycosidic bonds,...
The stabilities of theN-glycosidic bonds of three adenosine analogs were studied by means ofab initoquantum chemistry methods. TheN9-methoxymethyl derivatives were studied as model compounds representing nucleosides. The Gibbs free energies were estimated for all possible mono- and double-protonated ...
This leads us to ask: does a simpler, more direct reaction pathway exists which allows for the one-pot synthesis of nucleosides via formation of the β-glycosidic bond between separately preformed sugar and nucleobase moieties? The same question was asked by Orgel and collaborators more than 40 ...