Therefore, ischemia hasdoi:10.1016/S0735-1097(00)80005-4D.G. StraussP.M. Van DamT.H. LimG.S. WagnerJournal of the American College of CardiologyTomanek RJ: Myocardial Ischemia and Infarction. In Coronary Vasculature: Development, Structure-Function, and Adaptations . New York: Springer; 2013:189–220.
During approximately 2 weeks, the necrosis heals by fibrotic scar from the periphery toward the center of ischemia. This scar matures and remodels within 2 months following the myocardial infarction [1]. Ventricular arrhythmias complicate all phases of myocardial infarction and they can result in a...
Cheng Qian1, Dan Ding1, Bin-bin Wang1, Lei Chen2, Ke-Fang Guo3, Dehao Fu4, Bing Han5,Yu-Hua Liao1 &Yi-Mei Du1 Transient receptor potential vanilloid 4 (TRPV4) is a Ca2+-permeable nonselective cation channel and can be activated during ischemia/reperfusion (...
The risk of developing an adverse outcome-death, (re)infarction, or recurrent severe ischemia that required revascularizationranged from 5% with a score of 0 or 1 to 41% with a score of 6 or 7. The score was derived from data in the TIMI 11B (Thrombolysis In Myocardial Infarction 11B) t...
ST Elevation and non-ST Elevation MIs When myocardial blood supply is abruptly reduced or cut off to a region of the heart, a sequence of injurious events occur beginning with ischemia (inadequate tissue perfusion), followed by necrosis (infarction), and eventual fibrosis (scarring) if the bloo...
Sleep disorders increase the risk and mortality of heart disease, but the brain-heart interaction has not yet been fully elucidated. Cuproptosis is a copper-dependent type of cell death activated by the excessive accumulation of intracellular copper. Her
but attenuated ST-segment elevation after 55 min ischemia. Importantly, this effect was not due to altered blood flow into the ischaemic region [3,71]. The mechanism for this is not known but could potentially involve the parasympathetic nervous system, which is required to convey the signal of...
Infarction, death of tissue resulting from a failure of blood supply, commonly due to obstruction of a blood vessel by a blood clot or narrowing of the blood-vessel channel. The dead tissue is called an infarct. Myocardial infarction (heart attack)—deat
Myocardial ischemia-reperfusion injury refers to the damage and inflammatory response of myocardial cells caused by the reperfusion of blood and oxygen after myocardial ischemia. This condition typically arises in situations such as heart transplantation, myocardial infarction, acute onset of h...
‘burnout’cardiomyopathyoccurs in a small percentage of cats with HCM and is characterized bysystolic dysfunction, ventricular and atrial dilations, myofiber atrophy, and extensive myocardial replacement fibrosis (Figures 32–34). The latter is presumed to result frommyocardial ischemiafollowed by repair...