The poorly expanding apheresis products also contained less CD3+ cells (27.4±10.6% vs 59.7±19.5%; p=0.0045) and more CD56+ cells (26.9±14.5% vs 6.1±5.5%; p<0.001), but there was no difference in the quantity of CD19+ cells. The sum of the proportion of granulocytes and monocytes...
Myeloid progenitor cells in the peripheral blood of patients with hairy cell leukemia and other "leukemic" lymphoproliferative disorders U, Knapp W (1986) Myeloid progenitor cells in the peripheral blood of patients with hairy cell leukemia and other ‘Leukemic’ lymphoproliferative disorders... K ...
Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and monocytes with potent immunosuppressive activity. They are implicated in the regulation of immune responses in many pathological conditions and are closely associated with poor clinical outcomes in cancer. Recent studies hav...
Two subsets of dendritic cells are present in human cerebrospinal fluid Little is known about the presence of dendritic cells in the human CNS. To investigate the occurrence of dendritic cells in the CSF, paired blood/CSF sampl... P Mikhail,Huang Yu-Min,K Vasilios,... - 《Brain A Journal...
Myeloid cells were derived from neonatal cord blood by culture with granulocyte-macrophage colony-stimulating factor for approximately 8 days. The resultant cell population contained large adherent cells (diameter > or = microns), expressing formylated peptide receptors that were functionally coupled to ...
Myeloid-derived suppressor cells (MDSC) play an important role in tumor-mediated immune evasion. Levels of MDSC in peripheral blood are increased in patients with cancer, correlating with cancer stage and outcome. Studies have confirmed the associations between MDSC and various cytokines in the ...
cells (neutrophils, basophils, and eosinophils), monocytes and macrophages, microglia, dendritic cells, osteoclasts and mast cells. Platelets and red blood cells are also produced from the common myeloid progenitor. Neutrophils and lymphocytes are the most abundant white blood cells in the peripheral ...
AML progresses rapidly in the body. Simply put, the aberrantly proliferative and differentiated myeloid cells infiltrate into blood, marrow blood and other tissues, leading to impaired hematopoiesis and a variety of complications (i.e., systemic infection) that eventually threaten patients’ life2, 3...
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells Vascular endothelial growth factor (VEGF) is an essential regulator of normal and abnormal blood vessel growth. A monoclonal antibody (mAb) that targets VE... F Shojaei,X Wu,AK Malik,... - 《Nature Biotechnol...
Myeloid-derived suppressor cells (MDSCs) are present in large numbers in blood of mice and humans with cancer, and they strongly inhibit T-cell and natural killer (NK) cell responses, at young and old age. We found that a highly attenuated bacterium Listeria monocytogenes (Listeriaat)-infected...