Sevoflurane treatment enhanced the phosphorylation of NF-kappa B, and up-regulated the expressions of TLR4 and MyD88 (P < 0.05), which demonstrated that sevoflurane inhibited proliferation and differentiation of neuronal cells by activating TLR4/MyD88/NF-kappa B signaling both in vitro and vivo. ...
Huangfu W, Ma J, Zhang Y, Liu M, Liu B, Zhao J, Wang Z, Shi Y. Dietary Fiber-Derived Butyrate Alleviates Piglet Weaning Stress by Modulating the TLR4/MyD88/NF-κB Pathway. Nutrients. 2024; 16(11):1714. https://doi.org/10.3390/nu16111714 Chicago/Turabian Style Huangfu, Weikang,...
88 (MyD88), subsequently delaying the translocation of nuclear factor-kappa B (NF-κB) to the nucleus. Additionally, co-immunoprecipitation (Co-IP) experiments demonstrated that EPS-LM inhibited the binding of TLR4 to MyD88. The ability of EPS-LM to inhibit the TLR4/MyD88/NF-κB pathway, ...