Mycophenolic acid drug interactions (more detail)Does mycophenolic acid interact with my other drugs? Enter medications to view a detailed interaction report using our Drug Interaction Checker. Drug name Add a drug to check interactions Add
Mycophenolic acid (MPA) and trimethoprim-sulfamethoxazole (TMP-SMX) are commonly prescribed together in certain groups of patients, including solid organ transplant recipients. However, little is known about the pharmacokinetic drug鈥揹rug interactions (DDIs) between these two me...
Check interactions Compare alternatives Pricing & coupons Reviews (8) Drug images Dosage information During pregnancy Drug class: selective immunosuppressants En español Patient resources Mycophenolic acid drug information Mycophenolic Acid Delayed-Release Tablets Other brands Myfortic Professional resources Myco...
Objective: Mycophenolic acid (MPA) exposure is associated with clinical outcomes in hematopoietic cell transplant (HCT) recipients. Various drug interaction studies, predominantly in healthy volunteers or solid organ transplant recipients, have identified medications which impact MPA pharmacokinetics. Recipients...
The drug is cleared predominantly via the kidneys, and 95% of the administered dose appears in urine as 7-hydroxy mycophenolic acid glucuronide (MPAG). The current study was designed to unravel the renal excretory pathway of MPA and MPAG, and their potential drug-drug interactions. The role ...
Inhibition of intestinal and hepatic glucuronidation of mycophenolic acid by Ginkgo biloba extract and flavonoids. Herb-drug interactions have received more attention in recent years because of the widespread popularity of herbal supplements. However, there are limited ... MF Mohamed,RF Frye - 《Drug...
The lack of effect of mycophenolic acid on cardiac GTP levels is consistent with the absence of any pharmacological action on cardiac functions associated with receptor-G-protein-GTP interactions. The ability of the morpholinoethyl ester of mycophenolic acid (a clinically effective immunosuppressive ...
In vitro effects of mycophenolic acid on the nucleotide pool and on the expression of adhesion molecules of human umbilical vein endothelial cells The immunosuppressive drug mycophenolate mofetil (MMF) and its active metabolite mycophenolic acid (MPA) selectively inhibit inosine 5′-monophosphate dehy.....
When evaluating AGs, not only their own toxic potential but also the risk of drug–drug interactions (DDIs) should be considered. Show abstract Drugs that Act on the Immune System: Immunosuppressive and Immunostimulatory Drugs 2015, Side Effects of Drugs Annual Citation Excerpt : An in vitro ...
dehydrogenase,thereby suppressingthedenovosynthesisofguanosinnucleotidesin TandBlymphocytes.Thisleadstoanarrestofproliferation andfunctionofthesecells[4]. MPAisprimarilymetabolizedbyglucuronidationatthe phenolichydroxylgrouptoamycophenolicacidglucuronide (MPAG),whichisthemajorurinaryexcretionproductofthe drug[1,3]....