Quantitative multiplexed imaging technologies for single-cell analysis to assess predictive markers for immunotherapy in thoracic immuno-oncology: promises and challengesTUMOR MUTATIONAL BURDENTYRAMIDE SIGNAL AMPLIFICATIONARTIFICIAL-INTELLIGENCECANCERIMMUNOHISTOCHEMISTRY...
Recent advances in multiplexed imaging technologies promise to improve the understanding of the functional states of individual cells and the interactions between the cells in tissues. This often requires compilation of results from multiple samples. However, quantitative integration of information between ...
Magnetic Resonance ImagingImage Processing, Computer-AssistedNeoplasmsThe development of imaging technologies that have sufficient specificity and sensitivity to enable early, accurate detection of cancer and response to therapy has long been a goal in oncology. Various radiological techniques have been used...
The growing scale and dimensionality of multiplexed imaging require reproducible and comprehensive yet user-friendly computational pipelines. TRACERx-PHLEX performs deep learning-based cell segmentation (deep-imcyto), automated cell-type annotation (TYPE
improve the detection capability and allow for studying more targets in the same sample. “Another key benefit of quantum dots is that multiple probes can be excited with a single laser, which greatly simplifies experimental setup,” reports Kristie Krug, CEO and COO at Core Quantum Technologies....
Advancements in multiplexed tissue imaging technologies are vital in shaping our understanding of tissue microenvironmental influences in disease contexts. These technologies now allow us to relate the phenotype of individual cells to their higher-order roles in tissue organization and function. Multiplexed ...
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sensor, allowing it to be further used for ultrahigh-speed imaging when combined with high-speed cameras. This new 3D imaging paradigm opens an avenue for the development of high-speed or ultra-high-speed 3D imaging capabilities, thereby pushing the boundaries of current 3D imaging technologies. ...
Medical imaging technologies have undergone explosive growth over the past few decades and now play a central role in clinical oncology. Targeted magnetic resonance imaging (MRI) has emerged as a promising diagnostic approach offering high resolution depictions of pathological anatomy and the detection ...
enhances the concept of spatial parallelism of light, an idea initially explored in the 1980s through a technique called “shadow casting.” Although shadow casting offered valuable insights, its dependence on geometrical optics limited its flexibility and ability to integrate with other technologies. ...