Retrovirology 2010, 7:83 http://www.retrovirology.com/content/7/1/83 RESEARCH Open Access In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy Tanya Lynn Applegate1,2*, Donald John Birkett1,3, Glen John ...
Retrovirology 2010, 7:83 http://www.retrovirology.com/content/7/1/83 RESEARCH Open Access In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy Tanya Lynn Applegate1,2*, Donald John Birkett...
Birnaviruses form a distinct family of double-stranded RNA viruses infecting animals as different as vertebrates, mollusks, insects and rotifers. With such a wide host range, they constitute a good model for studying the adaptation to the host. Additiona
Technology for introduction of DNA into cells is well-known to those of skill in the art. Four general methods for delivering a gene into cells have been described: (1) chemical methods (Graham and Van der Eb,Virology,54(2): 536-539, 1973; Zatloukal et al.,Ann. N.Y. Acad. Sci.,...
wherein at least two copies of a sequence coding for the same epitope region of an organism such as virus or corresponding regions of different strains of the virus is placed in a single cassette; (3) transforming a suitable host with one or more copies of the cassette in order to ...
Persistent JC virus (JCV) infection is demonstrated by continuous shedding of the same JCV strains. J. Clin. Microbiol. 1997, 35, 1255–1257. [Google Scholar] [CrossRef] [PubMed] [Green Version] Del Valle, L.; Pina-Oviedo, S. Human polyomavirus JCPyV and its role in progressive ...
viruses Brief Report JCPyV miR-J1-5p in Urine of Natalizumab-Treated Multiple Sclerosis Patients Simone Agostini 1,* , Roberta Mancuso 1 , Andrea Saul Costa 1, Domenico Caputo 1 and Mario Clerici 1,2 1 IRCCS Fondazione Don Carlo Gnocchi ONLUS, 20148 Milan, Italy; rmancuso@dongnocchi.it (...
In the case of the virus rISAV-HPR0 R6, the deleted HPR region exposes the fusion protein cleavage sites. Still, as segment 5 is an HPR0, it does not have the IN4 insertion, which theoretically provides additional cleavage sites, meaning that activation of the protein is not possible. ...